Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CKV93_RS07635 Genome accession   NZ_LT906464
Coordinates   1549795..1550511 (+) Length   238 a.a.
NCBI ID   WP_095117455.1    Uniprot ID   A0A240C5L4
Organism   Staphylococcus muscae strain NCTC13833     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1544795..1555511
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV93_RS07610 (SAMEA4412661_01555) - 1545043..1546035 (-) 993 WP_095117451.1 SdrH family protein -
  CKV93_RS07615 (SAMEA4412661_01556) - 1546298..1547095 (+) 798 WP_095117452.1 carbon-nitrogen family hydrolase -
  CKV93_RS10800 - 1547311..1547388 (-) 78 WP_142380996.1 delta-lysin family phenol-soluble modulin -
  CKV93_RS07620 (SAMEA4412661_01557) - 1547743..1548309 (+) 567 WP_095117453.1 accessory gene regulator AgrB -
  CKV93_RS07625 (SAMEA4412661_01558) agrD 1548309..1548449 (+) 141 WP_229709407.1 cyclic lactone autoinducer peptide AgrD -
  CKV93_RS07630 (SAMEA4412661_01559) agrC 1548487..1549782 (+) 1296 WP_371866988.1 quorum-sensing sensor histidine kinase AgrC -
  CKV93_RS07635 (SAMEA4412661_01560) agrA 1549795..1550511 (+) 717 WP_095117455.1 quorum-sensing response regulator AgrA Regulator
  CKV93_RS07640 (SAMEA4412661_01561) - 1550564..1551511 (-) 948 WP_095117456.1 carbohydrate kinase -
  CKV93_RS07645 (SAMEA4412661_01562) - 1551504..1552997 (-) 1494 WP_095117457.1 sucrose-6-phosphate hydrolase -
  CKV93_RS07650 (SAMEA4412661_01563) - 1553012..1553995 (-) 984 WP_095117458.1 LacI family DNA-binding transcriptional regulator -
  CKV93_RS07655 (SAMEA4412661_01564) - 1554182..1554406 (-) 225 WP_095117459.1 sulfurtransferase TusA family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27711.52 Da        Isoelectric Point: 5.6230

>NTDB_id=1147753 CKV93_RS07635 WP_095117455.1 1549795..1550511(+) (agrA) [Staphylococcus muscae strain NCTC13833]
MKIFICEDDPKQRARMENIINTYIMIEEKPMEIALSTDNPYELIEASKTSSDVGCYFLDIQLESDINGIKVGSEIRQHDP
IGNIVYVTSHSELTYLTFVYKVAAMDFIFKDDPDQLQKRVIDCLETALNRLNLLTKEETVETLELKRGSGSEYVNYDEVM
FFESSPKSHRVIAHLDNRQVEFYGKLKELSQVDSRFFRCHNSFVLNRHNIANVEPKERTVHFKNGEHCYVSVRNIKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1147753 CKV93_RS07635 WP_095117455.1 1549795..1550511(+) (agrA) [Staphylococcus muscae strain NCTC13833]
ATGAAAATATTCATTTGCGAAGATGATCCAAAACAGCGTGCACGCATGGAAAATATCATCAACACATACATTATGATTGA
AGAAAAACCCATGGAAATTGCACTGTCAACGGACAATCCCTACGAACTGATAGAAGCCTCCAAAACGTCATCAGATGTTG
GCTGTTACTTTTTGGATATTCAATTAGAATCAGATATTAACGGTATAAAAGTCGGCAGTGAGATTCGACAACATGATCCA
ATTGGCAATATCGTTTATGTCACGAGTCACAGCGAACTCACCTATTTAACATTTGTATACAAAGTTGCTGCAATGGACTT
TATATTCAAAGATGACCCTGATCAACTTCAAAAACGAGTCATCGATTGTTTGGAAACAGCACTTAATCGCTTGAATTTGC
TAACTAAAGAAGAGACAGTAGAAACATTAGAATTAAAACGTGGGAGTGGTTCGGAATACGTCAACTATGATGAGGTGATG
TTTTTTGAATCCTCTCCAAAGTCACATCGTGTCATCGCACATTTAGACAATCGCCAAGTTGAATTTTATGGTAAATTAAA
AGAACTATCACAAGTCGACTCACGATTCTTCCGCTGTCATAACAGCTTCGTCCTTAACCGACATAACATCGCCAATGTCG
AGCCTAAAGAGAGAACTGTTCACTTCAAAAATGGTGAACATTGTTATGTCTCTGTGCGCAATATTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(153-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A240C5L4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

76.05

100

0.761
  comE/comE1 Streptococcus equinus JB1

34.4

100

0.361

Multiple sequence alignment