Detailed information    

insolico Bioinformatically predicted

Overview

Name   letS   Type   Regulator
Locus tag   CKW05_RS10740 Genome accession   NZ_LT906457
Coordinates   2384565..2387321 (+) Length   918 a.a.
NCBI ID   WP_058482311.1    Uniprot ID   A0A0W0Z965
Organism   Legionella spiritensis strain NCTC11990     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2379565..2392321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKW05_RS10720 (SAMEA4412668_02141) - 2379720..2380304 (-) 585 WP_058482314.1 hypothetical protein -
  CKW05_RS10725 (SAMEA4412668_02142) - 2380474..2381505 (+) 1032 WP_058482313.1 hypothetical protein -
  CKW05_RS10730 (SAMEA4412668_02143) - 2381511..2382962 (-) 1452 WP_058482312.1 YdiU family protein -
  CKW05_RS10735 (SAMEA4412668_02144) gltX 2382999..2384414 (-) 1416 WP_058482457.1 glutamate--tRNA ligase -
  CKW05_RS10740 (SAMEA4412668_02145) letS 2384565..2387321 (+) 2757 WP_058482311.1 two-component system sensor histidine kinase LetS Regulator
  CKW05_RS10745 (SAMEA4412668_02146) - 2387351..2388586 (+) 1236 WP_058482310.1 6-phosphofructokinase -
  CKW05_RS10750 (SAMEA4412668_02147) pilA2 2388702..2389109 (-) 408 WP_058482456.1 pilin Machinery gene
  CKW05_RS10755 (SAMEA4412668_02148) pilA2 2389217..2389624 (-) 408 WP_058482309.1 pilin Machinery gene
  CKW05_RS10760 (SAMEA4412668_02149) - 2389977..2390294 (+) 318 WP_058482308.1 BolA family transcriptional regulator -
  CKW05_RS10765 (SAMEA4412668_02150) - 2390287..2390730 (+) 444 WP_058482307.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  CKW05_RS10770 (SAMEA4412668_02151) - 2390804..2392201 (+) 1398 WP_058482455.1 APC family permease -

Sequence

Protein


Download         Length: 918 a.a.        Molecular weight: 103088.21 Da        Isoelectric Point: 6.8499

>NTDB_id=1147576 CKW05_RS10740 WP_058482311.1 2384565..2387321(+) (letS) [Legionella spiritensis strain NCTC11990]
MKGLGIKYQLRLTTLIPVLLVAVLFAVIYNGQFSKDLTQHMSRLGESYIRQLLPAAQLAMMRNDRRILQGLIDASTINPE
IISLAFYNADGQLIAYRGGKHSINKPIKPLEYTGDYIESTQTAPYSINFLAPITIPKYNLYTPGLFQSTPDITNLRPDDI
LGWLSIDLDTKSMIIKRYQMYIITIFITLVGLLVSLSIHYFLSRRLYLPIARLRRSMKQILSNEFETHIAVTSKGELGLV
EKGCAHLQKQYLDTVRDLNHHIEVATEDLQQSLELLEEKNIELTMEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKSSAQDLLTIINDILDYSKMDAGKLSLDCIPLDLRACIDEVLTLAAPNAHKKGIDLIPSTDI
AVPKTVLGDPIRIKQILTNLVNNAIKFTERGYVLIKTVVEQESEKDYSLCISVTDTGIGISAEDQTKLFNAFNQADTTIT
RRFGGSGLGLVICKKLAEEMKGRITLTSELHKGSTFTVRIRLEKFPAYEAEKHQNNRFDDLKAICFDDNPLHLEGICNGL
EYCGIHSVPVTTLKELEQALTERKDCKIALVNVNDGCEEQIAGILKNHTTPTILISKTVIHDPQSLGGCAFLFRPISIQK
LQDTIESLLNQKIHNKASMEANHELDKLRAQLRLSHPDVLIAEDNPVNRMLLQSFLNEGAQVETVQDGEEAVKASLGKRY
NIILLDLQMPKLGGIDAAKLIHQDSLLNKSTPIVIISADQVSLSADKLKQAGIHLCLQKPIEEKQFLTHLLQLLTKNKTI
AIDWQLCIQKVSGNQALAEEFLTRFVAELRKNRQEFIQLFHNKDIKNLEKAAHKLHGACCFCGVPRLQSQVTRLENQAGT
AQDIKELETAFAALIRCIDDVLDEFDNLYNTSSSDSQK

Nucleotide


Download         Length: 2757 bp        

>NTDB_id=1147576 CKW05_RS10740 WP_058482311.1 2384565..2387321(+) (letS) [Legionella spiritensis strain NCTC11990]
ATGAAAGGATTAGGCATCAAATACCAGTTGCGCCTGACTACTTTGATACCGGTATTGCTGGTCGCGGTACTGTTTGCCGT
GATCTATAACGGCCAGTTCAGCAAGGATTTAACGCAACATATGTCCCGTTTGGGCGAATCGTATATACGGCAACTTCTCC
CGGCAGCCCAGCTCGCCATGATGCGTAACGACCGACGTATTCTCCAGGGATTGATCGATGCCTCCACGATTAATCCGGAA
ATTATCTCACTGGCATTTTATAACGCGGACGGCCAGTTAATTGCTTATCGGGGAGGGAAACACTCCATTAACAAACCGAT
CAAACCCCTCGAATACACCGGAGACTACATCGAAAGCACCCAAACGGCCCCGTACAGTATTAATTTTCTGGCCCCGATTA
CCATCCCCAAATATAATCTCTACACTCCGGGACTCTTTCAATCCACACCGGATATCACCAACCTGCGCCCGGATGACATA
TTGGGATGGCTGTCTATTGATCTTGATACCAAGTCCATGATCATCAAGCGTTATCAAATGTATATCATCACCATTTTCAT
TACCCTCGTCGGCCTGTTGGTCAGCTTAAGCATCCATTATTTCCTTTCCAGGCGTTTATACCTGCCCATCGCCCGTTTAC
GGCGCAGCATGAAACAAATCCTGAGCAACGAATTTGAAACGCATATTGCGGTCACCAGCAAAGGCGAGCTGGGCCTCGTT
GAAAAAGGATGCGCCCACTTGCAAAAGCAATATCTCGATACCGTTCGCGATCTCAATCACCATATTGAAGTAGCGACGGA
AGATTTACAGCAAAGTCTTGAATTGCTGGAAGAAAAAAACATCGAACTCACTATGGAAAAGAAAAAGACGGAAGAGAAAA
GCCGTCAGAAATCCGAATTCATAGCCAATATGAGTCATGAAATCAGAACACCGATGAATGGTGTGATTGGCTTTACCAAT
GTTTTACTGGAAAGCAAGCTGGATCCATTGCAGCTGGATTATGTGAAAACCATCAAATCATCCGCCCAGGATTTATTAAC
CATTATCAACGACATTCTCGATTATTCCAAAATGGATGCCGGAAAACTAAGCCTGGACTGTATTCCTCTGGATTTGAGAG
CCTGCATCGATGAAGTGCTAACCCTGGCGGCTCCTAACGCCCATAAAAAAGGCATCGACCTGATTCCCTCAACGGATATC
GCCGTTCCTAAAACCGTCCTCGGCGATCCCATACGTATCAAGCAGATTCTCACTAATCTGGTCAACAACGCCATAAAATT
TACCGAGCGTGGCTATGTGCTGATAAAAACCGTCGTCGAACAGGAATCGGAAAAAGACTATTCCTTATGTATTTCCGTCA
CAGACACCGGCATCGGTATTTCAGCCGAAGATCAGACCAAACTGTTTAATGCCTTTAACCAGGCGGACACTACCATTACC
CGACGGTTCGGGGGATCCGGGCTTGGTCTGGTGATTTGCAAAAAACTGGCGGAGGAAATGAAAGGACGTATTACCCTGAC
CAGCGAACTGCACAAGGGTTCAACCTTCACCGTGCGGATCCGGCTTGAAAAATTCCCGGCGTATGAGGCGGAAAAGCATC
AAAATAACCGTTTTGATGATCTGAAAGCGATTTGTTTTGATGATAACCCCCTGCATCTGGAAGGTATCTGCAACGGGCTT
GAATACTGCGGTATCCATTCTGTTCCGGTAACGACTCTGAAAGAACTGGAACAGGCTTTAACGGAAAGAAAGGACTGTAA
AATAGCGTTGGTCAACGTCAATGACGGATGCGAGGAACAAATCGCCGGGATTTTGAAAAATCACACCACGCCAACTATTC
TCATATCCAAAACGGTCATTCATGATCCGCAATCACTGGGCGGCTGTGCCTTTTTATTTCGTCCAATCAGCATCCAGAAA
CTACAGGATACGATCGAATCACTGCTTAACCAAAAAATACACAACAAAGCGTCCATGGAAGCAAACCATGAACTGGACAA
ACTGCGCGCACAGCTTCGCCTTTCCCATCCGGATGTGTTAATTGCCGAAGACAATCCGGTCAACCGCATGCTTCTTCAAT
CATTCCTGAATGAAGGCGCCCAGGTTGAAACGGTACAAGACGGTGAGGAAGCCGTTAAGGCATCGCTTGGCAAACGCTAT
AATATTATTCTTCTTGATTTGCAAATGCCAAAACTGGGTGGTATTGACGCCGCGAAATTGATACATCAGGATTCATTACT
TAACAAATCAACACCGATTGTTATCATCAGCGCTGATCAAGTCAGCTTGTCCGCTGACAAACTGAAACAAGCCGGCATCC
ATCTCTGTCTGCAAAAACCCATTGAAGAAAAACAATTTCTGACTCATTTGCTGCAGTTACTGACCAAAAACAAAACCATT
GCCATTGACTGGCAACTCTGTATCCAGAAAGTTTCAGGAAATCAGGCGCTTGCCGAGGAATTTCTCACCCGCTTTGTTGC
CGAACTTCGTAAAAACCGTCAGGAATTTATCCAATTATTTCATAACAAGGATATTAAAAATCTGGAAAAAGCGGCCCATA
AACTTCATGGTGCCTGCTGTTTTTGCGGCGTTCCACGCCTGCAATCCCAGGTAACCCGTCTGGAAAACCAGGCCGGAACA
GCGCAGGATATTAAAGAACTCGAAACCGCATTCGCAGCTCTCATACGCTGTATTGATGACGTTCTGGATGAATTTGACAA
TTTATACAATACCAGTTCATCGGATTCACAAAAATAA

Domains

Predicted by InterproScan.

Hpt domain (Hpt)

(820-896)

His Kinase A (phospho-acceptor) domain (HisKA)

(297-361)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(408-523)

Response regulator receiver domain (Response_reg)

(679-789)

Single cache domain 4 (sCache_4)

(35-179)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0W0Z965

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letS Legionella pneumophila strain ERS1305867

68.456

99.455

0.681

Multiple sequence alignment