Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   CKW04_RS06820 Genome accession   NZ_LT906442
Coordinates   1455173..1456501 (+) Length   442 a.a.
NCBI ID   WP_058481187.1    Uniprot ID   A0A0W1A2N3
Organism   Legionella waltersii strain NCTC13017     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1450173..1461501
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKW04_RS06795 (SAMEA4504053_01385) - 1450650..1452125 (+) 1476 WP_058479482.1 tetratricopeptide repeat protein -
  CKW04_RS06800 (SAMEA4504053_01386) - 1452263..1452604 (+) 342 WP_083500099.1 endonuclease domain-containing protein -
  CKW04_RS06805 (SAMEA4504053_01387) - 1452628..1453068 (-) 441 WP_058481189.1 IS5 family transposase -
  CKW04_RS06810 (SAMEA4504053_01388) - 1453100..1453423 (-) 324 WP_095197513.1 transposase -
  CKW04_RS06815 (SAMEA4504053_01389) - 1453593..1455176 (+) 1584 WP_058481188.1 PAS domain-containing sensor histidine kinase -
  CKW04_RS06820 (SAMEA4504053_01390) pilR 1455173..1456501 (+) 1329 WP_058481187.1 sigma-54 dependent transcriptional regulator Regulator
  CKW04_RS06825 (SAMEA4504053_01391) - 1456742..1457224 (-) 483 WP_058481186.1 hypothetical protein -
  CKW04_RS06830 (SAMEA4504053_01392) - 1457447..1457692 (+) 246 WP_058481185.1 hypothetical protein -
  CKW04_RS06835 (SAMEA4504053_01393) - 1457711..1458412 (-) 702 WP_058481184.1 RES family NAD+ phosphorylase -
  CKW04_RS06840 (SAMEA4504053_01394) - 1458412..1458813 (-) 402 WP_231951030.1 MbcA/ParS/Xre antitoxin family protein -
  CKW04_RS06845 (SAMEA4504053_01395) - 1459334..1460212 (-) 879 WP_157737783.1 DUF2608 domain-containing protein -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49219.90 Da        Isoelectric Point: 5.9312

>NTDB_id=1147234 CKW04_RS06820 WP_058481187.1 1455173..1456501(+) (pilR) [Legionella waltersii strain NCTC13017]
MTTNKVLVIDDEPDIRELLTLTLSRMGLGCDAVESYQQGIELIQKNAYDLVLTDMRLSDGDGIDIVNFIQKSKPQLPVAV
ITAYGNIEGAVNTLKAGAFDYVSKPVDLRILKELVKTALSMQNPTAIEHQDALLVGESSIMKQLRENIHKLARSQAPVFI
QGDSGVGKELVAQLIHTNGPRKEKPFIPVNCGAIPSELMESEFFGHKKGSFTGAIADKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYETPVDVRILSASHKNLLEEISLGKFRQDLYYRVNVIELRVPTLVERLSDIPSLTEAIL
KKMAKNQNRQEVRINPACFDLLKQYDFPGNVRELENILERAMAMCEGDMIEPSDIHFPQTNTTRLGEAATISSSLDGYLQ
DHEKEIIIDALEKTKWNRTAAARLLGISFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=1147234 CKW04_RS06820 WP_058481187.1 1455173..1456501(+) (pilR) [Legionella waltersii strain NCTC13017]
ATGACTACGAATAAGGTACTTGTAATCGATGATGAGCCAGACATCAGAGAGTTATTAACTCTTACATTATCTCGTATGGG
ATTAGGTTGTGATGCTGTTGAAAGCTACCAACAAGGTATTGAGCTCATTCAAAAAAACGCCTATGACTTGGTGCTCACGG
ACATGCGTCTATCTGATGGAGATGGAATAGACATTGTCAATTTCATTCAAAAAAGCAAACCTCAATTGCCTGTGGCGGTG
ATTACGGCCTATGGAAATATTGAAGGAGCTGTTAATACTCTGAAAGCAGGTGCTTTTGATTATGTATCAAAGCCTGTAGA
TTTGAGAATCTTAAAGGAACTTGTTAAAACAGCATTATCCATGCAAAACCCCACAGCCATAGAACATCAGGATGCATTAT
TGGTTGGTGAAAGCAGCATTATGAAGCAATTGAGGGAGAACATTCACAAGTTAGCACGAAGCCAAGCTCCTGTATTTATT
CAAGGTGATTCTGGTGTTGGTAAGGAGTTGGTAGCCCAACTGATTCATACTAACGGGCCGAGAAAAGAGAAGCCATTTAT
ACCAGTAAACTGCGGTGCTATACCTTCTGAACTCATGGAGTCTGAGTTTTTCGGACATAAAAAAGGAAGTTTCACTGGGG
CAATAGCCGATAAAACAGGTTTATTTGTTGCCGCCCATGGAGGTACTTTATTTCTTGATGAAATTGCTGAGCTTCCTCTT
GCTATGCAGGTAAAATTATTACGTGCAATTCAGGAAAAGGCGATAAAGCCTATTGGTGAATTGTATGAAACACCTGTGGA
TGTAAGAATTTTAAGTGCAAGTCATAAGAACTTGCTTGAGGAGATCAGTCTTGGAAAGTTTAGGCAAGATCTCTACTATC
GAGTGAACGTCATTGAATTGCGAGTCCCGACTCTAGTTGAAAGATTATCTGACATTCCCAGCCTGACAGAAGCTATTTTA
AAGAAAATGGCAAAAAATCAAAATCGTCAGGAGGTTCGCATTAATCCAGCCTGTTTTGATTTATTAAAACAATACGATTT
CCCTGGAAATGTTAGGGAGTTAGAAAATATTCTCGAGCGCGCGATGGCCATGTGCGAAGGTGACATGATTGAACCTAGTG
ATATCCATTTTCCACAAACCAATACTACTCGCTTAGGCGAAGCTGCAACAATCTCCTCGAGTTTGGATGGCTACTTGCAA
GATCATGAAAAAGAAATCATTATCGATGCACTAGAGAAAACCAAATGGAATAGAACGGCAGCTGCCCGGTTATTGGGAAT
CAGTTTTAGGACCTTGCGCTATCGATTAAAAAAACTGGGACTGGATTAA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(134-300)

Bacterial regulatory protein, Fis family (HTH_8)

(400-439)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0W1A2N3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.551

100

0.6
  pilR Acinetobacter baumannii strain A118

47.403

100

0.495

Multiple sequence alignment