Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   VCBK1071_RS11175 Genome accession   NZ_LT897797
Coordinates   2427136..2427747 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae isolate Vibrio cholerae str. BC1071     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2422136..2432747
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VCBK1071_RS11155 (VCBK1071_02189) - 2422472..2423389 (-) 918 WP_000271070.1 ABC transporter ATP-binding protein -
  VCBK1071_RS11160 (VCBK1071_02190) - 2423770..2425416 (-) 1647 WP_101411035.1 SulP family inorganic anion transporter -
  VCBK1071_RS11165 (VCBK1071_02191) can 2425564..2426232 (+) 669 WP_001114116.1 carbonate dehydratase -
  VCBK1071_RS11170 (VCBK1071_02192) hpt 2426307..2426840 (-) 534 WP_101411037.1 hypoxanthine phosphoribosyltransferase -
  VCBK1071_RS11175 (VCBK1071_02193) hapR 2427136..2427747 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  VCBK1071_RS11185 (VCBK1071_02194) rsmI 2427956..2428822 (-) 867 WP_000131549.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  VCBK1071_RS11190 (VCBK1071_02195) - 2428892..2430697 (+) 1806 WP_001015477.1 penicillin-binding protein activator -
  VCBK1071_RS11195 (VCBK1071_02196) - 2430684..2431052 (+) 369 WP_032467958.1 YraN family protein -
  VCBK1071_RS11200 (VCBK1071_02197) - 2431056..2431646 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  VCBK1071_RS11205 (VCBK1071_02198) - 2431649..2432218 (+) 570 WP_000836325.1 BON domain-containing protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=1146671 VCBK1071_RS11175 WP_000340100.1 2427136..2427747(+) (hapR) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=1146671 VCBK1071_RS11175 WP_000340100.1 2427136..2427747(+) (hapR) [Vibrio cholerae isolate Vibrio cholerae str. BC1071]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACCTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAATTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709

Multiple sequence alignment