Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   BCM300_RS00235 Genome accession   NZ_LT837687
Coordinates   40350..41093 (+) Length   247 a.a.
NCBI ID   WP_000660557.1    Uniprot ID   -
Organism   Helicobacter pylori isolate BCM-300     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 35350..46093
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BCM300_RS00210 (BCM300_00040) panD 37499..37852 (+) 354 WP_000142286.1 aspartate 1-decarboxylase -
  BCM300_RS00215 (BCM300_00041) - 37855..38157 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  BCM300_RS00220 (BCM300_00042) - 38157..39161 (+) 1005 WP_089086474.1 PDZ domain-containing protein -
  BCM300_RS00225 (BCM300_00043) comB6 39169..40224 (+) 1056 WP_089086475.1 P-type conjugative transfer protein TrbL Machinery gene
  BCM300_RS00230 (BCM300_00044) comB7 40240..40353 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  BCM300_RS00235 (BCM300_00045) comB8 40350..41093 (+) 744 WP_000660557.1 type IV secretion system protein Machinery gene
  BCM300_RS00240 (BCM300_00046) comB9 41093..42079 (+) 987 WP_089086476.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  BCM300_RS00245 (BCM300_00047) comB10 42072..43208 (+) 1137 WP_089086477.1 DNA type IV secretion system protein ComB10 Machinery gene
  BCM300_RS00250 (BCM300_00048) - 43278..44690 (+) 1413 WP_089086478.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  BCM300_RS00255 (BCM300_00049) gmd 44731..45876 (+) 1146 WP_089086479.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28707.97 Da        Isoelectric Point: 8.9604

>NTDB_id=1146329 BCM300_RS00235 WP_000660557.1 40350..41093(+) (comB8) [Helicobacter pylori isolate BCM-300]
MKEKPFNSEQLIYLEELLSHQEKHLESKLSGFSVNDLDMQSVFRLERNRLKIAYRLLGLMSFIALVLAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APISRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=1146329 BCM300_RS00235 WP_000660557.1 40350..41093(+) (comB8) [Helicobacter pylori isolate BCM-300]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAGAG
CAAGCTTTCTGGTTTTTCGGTGAACGATTTGGACATGCAAAGCGTGTTTCGGCTAGAAAGGAACCGCTTGAAAATCGCTT
ACAGGCTTTTAGGTTTGATGAGCTTTATCGCGCTTGTCTTAGCGATCGTTTTAATCAGCATTCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGTATTAATCGCATTGACGATAAATCCCGCT
ATGAACTGGTGCGCTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAGCCCAAAACAGCATCTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCAGCTAAACTTTTGAATGAGAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGATTAGTAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

95.547

100

0.955

Multiple sequence alignment