Detailed information NTG1145840

Bioinformatically predicted

Overview

• Name: comB9
• Type: Machinery gene
• Locus tag: CS883_RS00230
• Genome accession: NZ_LT635476
• Coordinates: 41093..42079 (+)
• Length: 328 a.a.
• NCBI ID: WP_089086476.1
• Uniprot ID: A0A238GT51
• Organism: Helicobacter pylori isolate HE134/09
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 36093..47079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CS883_RS00200	panD	37499..37852 (+)	354	WP_000142286.1	aspartate 1-decarboxylase	-
CS883_RS00205	-	37855..38157 (+)	303	WP_000347926.1	YbaB/EbfC family nucleoid-associated protein	-
CS883_RS00210	-	38157..39161 (+)	1005	WP_089086474.1	PDZ domain-containing protein	-
CS883_RS00215	comB6	39169..40224 (+)	1056	WP_089086475.1	P-type conjugative transfer protein TrbL	Machinery gene
CS883_RS00220	comB7	40240..40353 (+)	114	WP_001217877.1	hypothetical protein	Machinery gene
CS883_RS00225	comB8	40350..41093 (+)	744	WP_000660557.1	type IV secretion system protein	Machinery gene
CS883_RS00230	comB9	41093..42079 (+)	987	WP_089086476.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
CS883_RS00235	comB10	42072..43208 (+)	1137	WP_089086477.1	DNA type IV secretion system protein ComB10	Machinery gene
CS883_RS00240	-	43278..44690 (+)	1413	WP_089086478.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
CS883_RS00245	gmd	44731..45876 (+)	1146	WP_089086479.1	GDP-mannose 4,6-dehydratase	-
CS883_RS00250	-	45869..46801 (+)	933	WP_001002481.1	GDP-L-fucose synthase family protein	-
CS883_RS08265	-	46829..47038 (-)	210	Protein_44	anthranilate synthase component I	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 37858.64 Da
• Isoelectric Point: 9.5584

>NTDB_id=1145840 CS883_RS00230 WP_089086476.1 41093..42079(+) (comB9) [Helicobacter pylori isolate HE134/09]
MRKVLYALIGFLLAFSVLKADDFLEEANETAPAHLNHPMQDLNAIQGSFFDKNRSKMSNTLNINYFQGQTYKIRLRYAMA
TLLFFSKPISDFVLGDKVGFDAKILESNDRILLIKPLQIGVDSNISVIDSEGKIFSFYVFSTTFTSSKHPNLQVFIEDKN
YYTNAFIKPQKENQENMAENAPKDAQKNNKPLKEEKEETKTPEEEVIIIGDNTNAMKIIKKDIQKGYKALKSSQRKWYCL
WACSKKSKLSLMPEEIFNDKQFTYFKFDKRLALSKFPVIYKVVDGYDNPVNTRIVGDYIIAEDVSAKWTLRLGKDYLCIR
FVKRSKGE

Nucleotide

• Length: 987 bp

>NTDB_id=1145840 CS883_RS00230 WP_089086476.1 41093..42079(+) (comB9) [Helicobacter pylori isolate HE134/09]
ATGCGTAAGGTTTTATACGCTCTCATTGGGTTTTTGTTGGCTTTTAGCGTTTTAAAAGCCGATGATTTTTTAGAAGAAGC
GAACGAAACAGCCCCGGCGCATTTAAACCACCCCATGCAGGATTTAAACGCCATTCAAGGGAGCTTTTTTGACAAAAACC
GCTCCAAAATGTCCAACACTTTGAATATTAATTATTTTCAAGGGCAAACCTATAAAATCCGCTTGCGTTATGCGATGGCG
ACCTTATTGTTTTTTTCAAAACCCATTAGCGATTTTGTTTTGGGGGATAAGGTGGGCTTTGATGCGAAAATCTTAGAGAG
CAACGATCGCATTTTACTCATCAAGCCTTTACAAATCGGCGTTGATTCCAATATCAGCGTGATTGATAGCGAGGGTAAGA
TTTTTTCTTTCTATGTGTTTTCTACCACTTTCACCAGCTCCAAACACCCTAATTTACAGGTTTTTATAGAAGATAAAAAC
TATTACACTAACGCTTTTATCAAGCCCCAAAAAGAAAATCAAGAAAATATGGCTGAAAATGCCCCTAAAGATGCCCAAAA
AAATAATAAGCCCCTAAAAGAAGAAAAAGAAGAAACTAAAACCCCAGAAGAAGAGGTGATAATTATTGGCGATAACACTA
ATGCGATGAAAATTATTAAAAAAGACATCCAAAAAGGCTATAAGGCTTTAAAAAGCTCTCAAAGGAAATGGTATTGTTTA
TGGGCTTGTTCTAAAAAATCCAAACTCTCCTTAATGCCTGAAGAAATCTTTAACGACAAACAATTCACTTATTTCAAATT
TGACAAAAGATTAGCGCTCTCTAAATTCCCGGTGATTTATAAGGTCGTTGATGGCTATGATAATCCGGTGAATACAAGGA
TTGTGGGCGATTACATTATCGCTGAAGACGTTTCGGCTAAATGGACTTTAAGGCTGGGTAAGGACTATTTGTGTATCCGT
TTTGTCAAAAGGAGCAAAGGTGAATAA

Domains

Predicted by InterproScan.

• Conjugal transfer protein (CagX) (62-319)

3D structure

• AlphaFold DB: A0A238GT51

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB9	Helicobacter pylori P1	90.854	100	0.909