Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   BT137_RS12900 Genome accession   NZ_LT632617
Coordinates   2849393..2850052 (-) Length   219 a.a.
NCBI ID   WP_061692755.1    Uniprot ID   -
Organism   Legionella pneumophila strain ST42 isolate ST42     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2844393..2855052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BT137_RS12885 (EUL120_02568) - 2845292..2845951 (+) 660 WP_013101910.1 hypothetical protein -
  BT137_RS12890 (EUL120_02569) lcl 2846119..2847501 (+) 1383 WP_014844754.1 collagen-like adhesin Lcl -
  BT137_RS12895 (EUL120_02570) uvrC 2847525..2849381 (-) 1857 WP_014844755.1 excinuclease ABC subunit UvrC -
  BT137_RS12900 (EUL120_02571) letA 2849393..2850052 (-) 660 WP_061692755.1 two-component system response regulator LetA Regulator
  BT137_RS12905 (EUL120_02572) phhA 2850177..2850995 (-) 819 WP_014844756.1 phenylalanine 4-monooxygenase -
  BT137_RS12910 (EUL120_02573) - 2851435..2852532 (+) 1098 WP_038839657.1 competence/damage-inducible protein A -
  BT137_RS12915 (EUL120_02574) cgtA 2852491..2853516 (-) 1026 WP_027266284.1 Obg family GTPase CgtA -
  BT137_RS12920 (EUL120_02575) rpmA 2853731..2854009 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  BT137_RS12925 (EUL120_02576) rplU 2854022..2854333 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24538.48 Da        Isoelectric Point: 5.1572

>NTDB_id=1145634 BT137_RS12900 WP_061692755.1 2849393..2850052(-) (letA) [Legionella pneumophila strain ST42 isolate ST42]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKAIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQEPQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1145634 BT137_RS12900 WP_061692755.1 2849393..2850052(-) (letA) [Legionella pneumophila strain ST42 isolate ST42]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTGGTTGCAGATGCTGAAAGTGGGGAGCAGGCTTTAGCTTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGCTTAAAAAAAACAAACCCAAATATTAAAGCCATAGCC
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAATCAGG
GGCTGAAGAAATGGCTGCTGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATTGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGCCTCAAGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACGAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGTTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAACACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment