Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   H044120014_RS13950 Genome accession   NZ_LT632616
Coordinates   3068958..3069617 (-) Length   219 a.a.
NCBI ID   WP_011947563.1    Uniprot ID   -
Organism   Legionella pneumophila strain ST37 isolate ST37     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3063958..3074617
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H044120014_RS13935 (BT148_RS14025) - 3064992..3065651 (+) 660 WP_011947560.1 hypothetical protein -
  H044120014_RS13940 (BT148_RS14030) lcl 3065819..3067066 (+) 1248 WP_040185895.1 collagen-like adhesin Lcl -
  H044120014_RS13945 (BT148_RS14035) uvrC 3067090..3068946 (-) 1857 WP_011947562.1 excinuclease ABC subunit UvrC -
  H044120014_RS13950 (BT148_RS14040) letA 3068958..3069617 (-) 660 WP_011947563.1 two-component system response regulator LetA Regulator
  H044120014_RS13955 (BT148_RS14045) phhA 3069742..3070560 (-) 819 WP_011947564.1 phenylalanine 4-monooxygenase -
  H044120014_RS13960 (BT148_RS14050) - 3070999..3072096 (+) 1098 WP_011947565.1 competence/damage-inducible protein A -
  H044120014_RS13965 (BT148_RS14055) cgtA 3072055..3073080 (-) 1026 WP_011947566.1 Obg family GTPase CgtA -
  H044120014_RS13970 (BT148_RS14060) rpmA 3073295..3073573 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  H044120014_RS13975 (BT148_RS14065) rplU 3073586..3073897 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24566.53 Da        Isoelectric Point: 5.1572

>NTDB_id=1145593 H044120014_RS13950 WP_011947563.1 3068958..3069617(-) (letA) [Legionella pneumophila strain ST37 isolate ST37]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQEPQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1145593 H044120014_RS13950 WP_011947563.1 3068958..3069617(-) (letA) [Legionella pneumophila strain ST37 isolate ST37]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCTTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGCTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCC
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAATCAGG
GGCTGAAGAAATGGCTGCTGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATTGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGCCTCAGGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACGAGCGGCATGAATGTACAAGACATTGCTGATAGATTGTTTTTAAGTAGTAAAACCATCAATGGTTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAACACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

100

100

1
  letA Legionella pneumophila strain ERS1305867

100

100

1

Multiple sequence alignment