Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   BQ6063_RS06005 Genome accession   NZ_LT632615
Coordinates   1309537..1310865 (+) Length   442 a.a.
NCBI ID   WP_027226200.1    Uniprot ID   -
Organism   Legionella pneumophila strain ST23 isolate ST23     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1304537..1315865
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BQ6063_RS05985 (EUL28_01179) amrS 1304662..1305738 (+) 1077 WP_027220760.1 AmmeMemoRadiSam system radical SAM enzyme -
  BQ6063_RS05990 (EUL28_01180) - 1305797..1306216 (+) 420 WP_011213527.1 lpg1171 family Dot/Icm T4SS effector -
  BQ6063_RS05995 (EUL28_01181) lidL 1306371..1307855 (+) 1485 WP_072356157.1 Dot/Icm type IV secretion system effector LidL -
  BQ6063_RS06000 (EUL28_01182) - 1307954..1309540 (+) 1587 WP_061690501.1 sensor histidine kinase -
  BQ6063_RS06005 (EUL28_01183) pilR 1309537..1310865 (+) 1329 WP_027226200.1 sigma-54-dependent transcriptional regulator Regulator
  BQ6063_RS06010 (EUL28_01184) - 1311292..1311537 (+) 246 WP_011213531.1 hypothetical protein -
  BQ6063_RS06015 (EUL28_01185) - 1311732..1312667 (-) 936 WP_027220757.1 alpha/beta fold hydrolase -
  BQ6063_RS06020 (EUL28_01186) - 1312946..1314382 (-) 1437 WP_027226716.1 M48 family metalloprotease -
  BQ6063_RS06025 (EUL28_01187) ribD 1314445..1315518 (+) 1074 WP_027220755.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49270.26 Da        Isoelectric Point: 6.9042

>NTDB_id=1145528 BQ6063_RS06005 WP_027226200.1 1309537..1310865(+) (pilR) [Legionella pneumophila strain ST23 isolate ST23]
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGVEIVKFIQKYKPQMPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKPDEDLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHVNGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGAFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPGVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=1145528 BQ6063_RS06005 WP_027226200.1 1309537..1310865(+) (pilR) [Legionella pneumophila strain ST23 isolate ST23]
ATGACCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCACGTATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTGTAGAAATTGTTAAATTCATTCAGAAATACAAACCGCAGATGCCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCACCTACCGAGAAGCCTGATGAAGATCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCAGGTGTTGGAAAAGAATTGGTCGCTCAGTTGATCCATGTTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGCGCAATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTAAAATTGCTACGTGCCATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAGTTAATGCAGGGGCATTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAGTTATCTAAAAATCAAAACAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATCCTCGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTGCCAAGAACAACAATAACCCCAGGTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(399-439)

Sigma-54 interaction domain (Sigma54_activat)

(134-300)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.551

100

0.6
  pilR Acinetobacter baumannii strain A118

48.584

100

0.505

Multiple sequence alignment