Detailed information
Bioinformatically predicted
Overview
| Name | amiC | Type | Regulator |
| Locus tag | STACADC2_RS06510 | Genome accession | NZ_LT604076 |
| Coordinates | 1221672..1223165 (-) | Length | 497 a.a. |
| NCBI ID | WP_002946410.1 | Uniprot ID | Q5M3H4 |
| Organism | Streptococcus thermophilus strain ACA-DC | ||
| Function | internalize XIP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1203200..1272982 | 1221672..1223165 | within | 0 |
Gene organization within MGE regions
Location: 1203200..1272982
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| STACADC2_RS06420 (STACADC2_1213) | liaF | 1203208..1203906 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| STACADC2_RS10085 (STACADC2_1214) | - | 1204161..1204328 (-) | 168 | WP_224103618.1 | potassium channel family protein | - |
| STACADC2_RS06430 (STACADC2_1216) | stkP/pknB | 1204966..1206837 (-) | 1872 | WP_087010057.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| STACADC2_RS06435 (STACADC2_1217) | - | 1206837..1207574 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| STACADC2_RS06440 (STACADC2_1218) | rsmB | 1207618..1208940 (-) | 1323 | WP_087010267.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| STACADC2_RS06445 (STACADC2_1219) | fmt | 1208930..1209865 (-) | 936 | WP_002946883.1 | methionyl-tRNA formyltransferase | - |
| STACADC2_RS06450 (STACADC2_1220) | - | 1209883..1212279 (-) | 2397 | WP_087010058.1 | primosomal protein N' | - |
| STACADC2_RS06455 (STACADC2_1221) | rpoZ | 1212421..1212735 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| STACADC2_RS06460 (STACADC2_1222) | gmk | 1212757..1213386 (-) | 630 | WP_002951416.1 | guanylate kinase | - |
| STACADC2_RS06465 (STACADC2_1223) | ftsY | 1213612..1215003 (-) | 1392 | WP_087010059.1 | signal recognition particle-docking protein FtsY | - |
| STACADC2_RS06470 (STACADC2_1224) | - | 1215017..1215832 (-) | 816 | WP_087010060.1 | Cof-type HAD-IIB family hydrolase | - |
| STACADC2_RS06475 (STACADC2_1225) | - | 1215825..1216619 (-) | 795 | WP_087010061.1 | HAD-IIB family hydrolase | - |
| STACADC2_RS06480 (STACADC2_1226) | - | 1216802..1217179 (+) | 378 | WP_087010062.1 | GntR family transcriptional regulator | - |
| STACADC2_RS06485 (STACADC2_1227) | - | 1217184..1217882 (+) | 699 | WP_087010063.1 | ABC transporter ATP-binding protein | - |
| STACADC2_RS06490 (STACADC2_1228) | - | 1217894..1218679 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| STACADC2_RS06495 (STACADC2_1229) | amiF | 1218729..1219658 (-) | 930 | WP_087010064.1 | ATP-binding cassette domain-containing protein | Regulator |
| STACADC2_RS06500 (STACADC2_1230) | amiE | 1219651..1220736 (-) | 1086 | WP_011226304.1 | ABC transporter ATP-binding protein | Regulator |
| STACADC2_RS06505 (STACADC2_1231) | amiD | 1220746..1221672 (-) | 927 | WP_002946409.1 | oligopeptide ABC transporter permease OppC | Regulator |
| STACADC2_RS06510 (STACADC2_1232) | amiC | 1221672..1223165 (-) | 1494 | WP_002946410.1 | ABC transporter permease | Regulator |
| STACADC2_RS06515 (STACADC2_1233) | amiA | 1223227..1225194 (-) | 1968 | WP_087010065.1 | peptide ABC transporter substrate-binding protein | Regulator |
| STACADC2_RS06520 (STACADC2_1234) | - | 1225580..1226781 (+) | 1202 | Protein_1196 | ISL3 family transposase | - |
| STACADC2_RS06525 (STACADC2_1235) | amiA3 | 1226826..1228799 (-) | 1974 | WP_087010066.1 | peptide ABC transporter substrate-binding protein | Regulator |
| STACADC2_RS09380 | - | 1229003..1229193 (-) | 191 | Protein_1198 | IS3 family transposase | - |
| STACADC2_RS09385 (STACADC2_1236) | - | 1229187..1229597 (-) | 411 | Protein_1199 | ATP-binding cassette domain-containing protein | - |
| STACADC2_RS09590 (STACADC2_1237) | - | 1229626..1229943 (-) | 318 | Protein_1200 | TatD family hydrolase | - |
| STACADC2_RS06540 (STACADC2_1238) | - | 1230292..1231497 (+) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| STACADC2_RS06545 | - | 1231544..1232895 (-) | 1352 | Protein_1202 | IS3 family transposase | - |
| STACADC2_RS06550 (STACADC2_1242) | pta | 1232981..1233964 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| STACADC2_RS06555 (STACADC2_1243) | - | 1233978..1234874 (-) | 897 | WP_087010067.1 | RluA family pseudouridine synthase | - |
| STACADC2_RS06560 (STACADC2_1244) | - | 1234871..1235707 (-) | 837 | WP_087010068.1 | NAD kinase | - |
| STACADC2_RS06565 (STACADC2_1245) | - | 1235679..1236353 (-) | 675 | WP_002951443.1 | GTP pyrophosphokinase family protein | - |
| STACADC2_RS06570 (STACADC2_1246) | - | 1236449..1237024 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| STACADC2_RS06575 (STACADC2_1247) | - | 1237387..1238358 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| STACADC2_RS06580 (STACADC2_1248) | - | 1238362..1239474 (+) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| STACADC2_RS06585 (STACADC2_1249) | - | 1239476..1239823 (+) | 348 | WP_011226321.1 | DUF1831 domain-containing protein | - |
| STACADC2_RS06590 (STACADC2_1250) | - | 1239968..1240627 (+) | 660 | WP_087010069.1 | redox-sensing transcriptional repressor Rex | - |
| STACADC2_RS06595 (STACADC2_1251) | - | 1240620..1241315 (+) | 696 | WP_002951449.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| STACADC2_RS06600 (STACADC2_1252) | radC | 1241368..1242054 (-) | 687 | WP_087010070.1 | RadC family protein | - |
| STACADC2_RS06605 (STACADC2_1253) | - | 1242103..1243887 (-) | 1785 | WP_087010071.1 | rhamnan synthesis F family protein | - |
| STACADC2_RS06610 (STACADC2_1254) | - | 1243884..1244939 (-) | 1056 | WP_002948022.1 | glycosyltransferase family 2 protein | - |
| STACADC2_RS06615 (STACADC2_1255) | - | 1244959..1246164 (-) | 1206 | WP_014727633.1 | ABC transporter ATP-binding protein | - |
| STACADC2_RS06620 (STACADC2_1256) | - | 1246164..1246973 (-) | 810 | WP_002948020.1 | ABC transporter permease | - |
| STACADC2_RS06625 (STACADC2_1257) | - | 1246957..1247913 (-) | 957 | WP_011226328.1 | glycosyltransferase family 2 protein | - |
| STACADC2_RS06630 (STACADC2_1258) | cps2T | 1247910..1249058 (-) | 1149 | WP_087010072.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| STACADC2_RS06635 (STACADC2_1259) | - | 1249165..1250706 (-) | 1542 | WP_087010073.1 | DUF2142 domain-containing protein | - |
| STACADC2_RS06640 (STACADC2_1260) | - | 1250709..1251716 (-) | 1008 | WP_087010074.1 | glycosyltransferase family 2 protein | - |
| STACADC2_RS06645 (STACADC2_1261) | - | 1251716..1252990 (-) | 1275 | WP_087010075.1 | lipopolysaccharide biosynthesis protein | - |
| STACADC2_RS06650 (STACADC2_1262) | - | 1252983..1253315 (-) | 333 | WP_011226332.1 | DUF2304 domain-containing protein | - |
| STACADC2_RS06655 (STACADC2_1263) | - | 1253321..1254016 (-) | 696 | WP_172838695.1 | glycosyltransferase family 2 protein | - |
| STACADC2_RS06660 (STACADC2_1264) | rfbD | 1254093..1254944 (-) | 852 | WP_087010077.1 | dTDP-4-dehydrorhamnose reductase | - |
| STACADC2_RS10315 | - | 1255021..1255752 (-) | 732 | WP_269456722.1 | DUF6056 family protein | - |
| STACADC2_RS10320 | - | 1255778..1256348 (-) | 571 | Protein_1227 | DUF6056 family protein | - |
| STACADC2_RS06670 (STACADC2_1267) | - | 1256461..1257387 (-) | 927 | WP_087010078.1 | glycosyltransferase family 2 protein | - |
| STACADC2_RS06675 (STACADC2_1268) | - | 1257397..1257732 (-) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| STACADC2_RS06680 (STACADC2_1269) | rpoD | 1257786..1258895 (-) | 1110 | WP_011226338.1 | RNA polymerase sigma factor RpoD | - |
| STACADC2_RS06685 (STACADC2_1270) | dnaG | 1258899..1260710 (-) | 1812 | WP_011681448.1 | DNA primase | - |
| STACADC2_RS06690 (STACADC2_1271) | mscL | 1260853..1260933 (+) | 81 | Protein_1232 | large conductance mechanosensitive channel protein MscL | - |
| STACADC2_RS06695 (STACADC2_1272) | rpsU | 1261092..1261268 (-) | 177 | WP_011681449.1 | 30S ribosomal protein S21 | - |
| STACADC2_RS06700 (STACADC2_1273) | - | 1261463..1262257 (-) | 795 | WP_023909836.1 | ABC transporter substrate-binding protein | - |
| STACADC2_RS06705 (STACADC2_1274) | - | 1262319..1263428 (-) | 1110 | WP_087010079.1 | aminotransferase | - |
| STACADC2_RS06710 (STACADC2_1275) | - | 1263775..1264572 (-) | 798 | WP_087010080.1 | transporter substrate-binding domain-containing protein | - |
| STACADC2_RS06715 (STACADC2_1276) | - | 1264569..1265399 (-) | 831 | WP_087010081.1 | transporter substrate-binding domain-containing protein | - |
| STACADC2_RS06720 (STACADC2_1277) | - | 1265612..1266076 (-) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| STACADC2_RS06725 (STACADC2_1278) | uvrB | 1266121..1268112 (-) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| STACADC2_RS06730 (STACADC2_1279) | - | 1268259..1268726 (-) | 468 | WP_087010082.1 | hypothetical protein | - |
| STACADC2_RS10440 (STACADC2_1280) | - | 1268799..1269734 (-) | 936 | Protein_1241 | CPBP family intramembrane glutamic endopeptidase | - |
| STACADC2_RS06745 (STACADC2_1281) | - | 1269934..1272144 (+) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| STACADC2_RS06750 (STACADC2_1282) | - | 1272144..1272884 (+) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 497 a.a. Molecular weight: 55751.62 Da Isoelectric Point: 10.0618
>NTDB_id=1145097 STACADC2_RS06510 WP_002946410.1 1221672..1223165(-) (amiC) [Streptococcus thermophilus strain ACA-DC]
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNSQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
MKKYILLRTLRSLLSIFVVTALTYTIIYTMVPRRLIFRQDPNYNKIAKTADSKANYENTIYERLGYIDYYDTKELQEKAS
SLDKSVTTKPTKENKAIYQKYVDSLGRGWRLHQFKQSKQFYATRDVPVLERVFGFYTHLFEFDNTGWVKDKTNPNLKRYI
RIENDPAIGWSVVGSGTKHKYLLYFNSQFPFVHQNFVKMNLGTSYPTYAEQGVLDVITQGQGQTKSSVVNFPTGKKISSV
DIYSRTYKSPSQADARDRSYYGNDPYTATKSRYQYPSMVTSSAIAGLIGLVLSYALAIPLGSYMALFKNTIFDSVSTGVL
TFLLSLPTIALVYIIRLIGSEIGLPDSFPILGAGDWRSYVLPSVILGLLSTPGLAIWIRRYMIDLQSQDFVRFARAKGLS
EQEISNKHILKNAMVSLVSGIPASIVGVITGATLTETIFAYPGMGKMLIDSVRASNNAMVVGLVFIFTALSIFSLLVGDI
LMTIIDPRIKLTSKGGK
Nucleotide
Download Length: 1494 bp
>NTDB_id=1145097 STACADC2_RS06510 WP_002946410.1 1221672..1223165(-) (amiC) [Streptococcus thermophilus strain ACA-DC]
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCAAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGTTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCACAAATATTTGCTTTACTTTAACAG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAATCTTGGAACTTCATACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTATTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATTTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTTGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
ATGAAAAAATACATTTTATTGAGAACACTCCGTTCTCTATTGTCAATATTTGTCGTGACGGCTTTGACCTACACGATTAT
CTATACCATGGTGCCGAGGCGTCTGATTTTCAGACAAGACCCAAACTACAACAAGATTGCTAAGACAGCTGATTCTAAGG
CTAACTATGAAAATACAATCTATGAACGTTTGGGTTACATTGATTACTATGACACCAAGGAGTTGCAGGAGAAAGCTAGC
TCCCTTGATAAGTCAGTAACCACTAAGCCAACAAAAGAAAATAAGGCTATCTACCAAAAATATGTGGATAGTTTAGGACG
TGGTTGGCGTTTGCATCAGTTCAAGCAAAGTAAACAATTCTATGCGACACGTGATGTGCCAGTGCTTGAACGTGTGTTTG
GCTTCTATACGCACCTCTTTGAATTTGACAATACTGGATGGGTTAAAGATAAAACAAATCCAAACTTGAAGCGTTATATC
CGTATTGAAAATGACCCAGCTATCGGTTGGTCAGTTGTTGGTTCAGGGACTAAGCACAAATATTTGCTTTACTTTAACAG
TCAGTTCCCATTTGTTCACCAAAACTTTGTGAAGATGAATCTTGGAACTTCATACCCAACTTATGCTGAGCAAGGTGTTC
TTGATGTTATTACACAAGGCCAAGGACAGACAAAAAGCTCTGTGGTTAACTTCCCTACTGGTAAGAAAATATCTTCAGTA
GATATCTATTCTCGTACTTATAAATCACCAAGTCAGGCTGACGCTAGAGATCGTTCTTACTATGGAAATGATCCATACAC
AGCTACCAAGAGTCGTTATCAATACCCATCAATGGTGACAAGTTCTGCCATTGCAGGTTTGATTGGTTTGGTCTTGTCTT
ATGCTTTGGCAATTCCATTGGGATCATACATGGCACTCTTTAAAAACACAATTTTTGATAGTGTGTCAACAGGTGTCTTG
ACTTTCTTGCTTTCACTACCAACCATCGCCTTGGTTTATATCATTCGTTTGATTGGTTCTGAGATTGGTCTTCCAGATTC
CTTCCCTATCTTGGGTGCAGGTGACTGGCGTTCATACGTCTTGCCATCTGTTATTCTCGGTCTCTTGTCAACACCAGGTC
TTGCGATTTGGATTCGTCGTTACATGATTGACTTGCAATCACAAGACTTTGTTCGTTTTGCACGTGCCAAAGGGTTGTCA
GAACAAGAAATTTCAAATAAACACATTTTAAAAAACGCTATGGTTTCCTTGGTTTCAGGGATCCCAGCATCTATTGTTGG
GGTTATCACAGGGGCAACCTTGACAGAAACAATCTTCGCCTACCCTGGTATGGGTAAAATGTTGATCGATTCTGTTCGTG
CTTCTAATAATGCTATGGTCGTTGGGCTGGTATTTATTTTTACAGCTCTCTCCATCTTCTCATTGCTTGTGGGTGATATC
CTTATGACTATTATTGACCCACGTATCAAATTGACATCTAAAGGAGGTAAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| amiC | Streptococcus thermophilus LMG 18311 |
100 |
100 |
1 |
| amiC | Streptococcus thermophilus LMD-9 |
99.195 |
100 |
0.992 |
| amiC | Streptococcus salivarius strain HSISS4 |
97.384 |
100 |
0.974 |