Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   BN8422_RS02895 Genome accession   NZ_LT598688
Coordinates   570761..571330 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate Sa_Newman_UoM     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 565761..576330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BN8422_RS02870 cysE 566974..567621 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  BN8422_RS02875 cysS 567605..569005 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  BN8422_RS02880 - 568998..569402 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  BN8422_RS02885 rlmB 569410..570156 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  BN8422_RS02890 - 570156..570680 (+) 525 WP_000664738.1 NYN domain-containing protein -
  BN8422_RS02895 sigH 570761..571330 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  BN8422_RS15115 rpmG 571445..571588 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  BN8422_RS02900 secE 571644..571826 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  BN8422_RS02905 nusG 571839..572387 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  BN8422_RS02910 rplK 572568..572990 (+) 423 WP_001085794.1 50S ribosomal protein L11 -
  BN8422_RS02915 rplA 573198..573890 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  BN8422_RS02920 rplJ 574162..574662 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  BN8422_RS02925 rplL 574705..575073 (+) 369 WP_001273585.1 50S ribosomal protein L7/L12 -
  BN8422_RS02930 - 575248..575856 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1144809 BN8422_RS02895 WP_000872873.1 570761..571330(+) (sigH) [Staphylococcus aureus isolate Sa_Newman_UoM]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1144809 BN8422_RS02895 WP_000872873.1 570761..571330(+) (sigH) [Staphylococcus aureus isolate Sa_Newman_UoM]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment