Detailed information NTG1144507

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: C7S04_RS10035
• Genome accession: NZ_LT592159
• Coordinates: 1702106..1702966 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain WHO_U
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1697106..1707966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7S04_RS10015 (WHOU_01875C)	dapD	1697616..1698437 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
C7S04_RS10020 (WHOU_01876C)	pgi	1698647..1700290 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
C7S04_RS10030 (WHOU_01877)	pilG	1700800..1702032 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
C7S04_RS10035 (WHOU_01878)	pilD	1702106..1702966 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
C7S04_RS10040 (WHOU_01879)	coaE	1702963..1703595 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
C7S04_RS10045 (WHOU_01880)	-	1703588..1703797 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
C7S04_RS10050 (WHOU_01881C)	pilF	1703883..1705559 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
C7S04_RS10065 (WHOU_01883C)	-	1705897..1706343 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
C7S04_RS10070 (WHOU_01884C)	-	1706347..1707321 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
C7S04_RS10080 (WHOU_01885)	rplU	1707545..1707853 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=1144507 C7S04_RS10035 WP_003689814.1 1702106..1702966(+) (pilD) [Neisseria gonorrhoeae strain WHO_U]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=1144507 C7S04_RS10035 WP_003689814.1 1702106..1702966(+) (pilD) [Neisseria gonorrhoeae strain WHO_U]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441