Detailed information NTG1144370

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: C7R99_RS09960
• Genome accession: NZ_LT592153
• Coordinates: 1696658..1697518 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain WHO_Z
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1691658..1702518

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7R99_RS09940 (WHOZ_01864C)	dapD	1692168..1692989 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
C7R99_RS09945 (WHOZ_01865C)	pgi	1693199..1694842 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
C7R99_RS09955 (WHOZ_01866)	pilG	1695352..1696584 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
C7R99_RS09960 (WHOZ_01867)	pilD	1696658..1697518 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
C7R99_RS09965 (WHOZ_01868)	coaE	1697515..1698147 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
C7R99_RS09970 (WHOZ_01869)	-	1698140..1698349 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
C7R99_RS09975 (WHOZ_01870C)	pilF	1698435..1700111 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
C7R99_RS09990 (WHOZ_01872C)	-	1700449..1700895 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
C7R99_RS09995 (WHOZ_01873C)	-	1700899..1701873 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
C7R99_RS10005 (WHOZ_01874)	rplU	1702097..1702405 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=1144370 C7R99_RS09960 WP_003689814.1 1696658..1697518(+) (pilD) [Neisseria gonorrhoeae strain WHO_Z]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=1144370 C7R99_RS09960 WP_003689814.1 1696658..1697518(+) (pilD) [Neisseria gonorrhoeae strain WHO_Z]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441