Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   E4V86_RS10225 Genome accession   NZ_LT591910
Coordinates   1737640..1738893 (-) Length   417 a.a.
NCBI ID   WP_047919725.1    Uniprot ID   A0AAX2TQK3
Organism   Neisseria gonorrhoeae strain WHO N     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1732640..1743893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4V86_RS10160 (WHON_01906) pilE 1732804..1733229 (+) 426 WP_134472171.1 pilin Machinery gene
  E4V86_RS14015 - 1733367..1733470 (+) 104 Protein_1759 pilin -
  E4V86_RS14020 - 1734023..1734412 (+) 390 Protein_1760 pilin -
  E4V86_RS14025 - 1734452..1734778 (+) 327 Protein_1761 pilin -
  E4V86_RS13425 - 1734797..1735126 (+) 330 Protein_1762 pilin -
  E4V86_RS10200 (WHON_01908) - 1735258..1735659 (+) 402 WP_269472848.1 pilin -
  E4V86_RS10210 (WHON_01909) - 1735791..1736177 (+) 387 Protein_1764 pilin -
  E4V86_RS14480 - 1736587..1736721 (+) 135 WP_256344619.1 hypothetical protein -
  E4V86_RS10220 (WHON_01910) - 1736706..1737371 (+) 666 WP_144894360.1 opacity family porin -
  E4V86_RS10225 (WHON_01911C) pilA 1737640..1738893 (-) 1254 WP_047919725.1 signal recognition particle-docking protein FtsY Machinery gene
  E4V86_RS10230 (WHON_01912) msrAB 1739039..1740607 (+) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  E4V86_RS10235 (WHON_01913C) - 1740691..1741173 (-) 483 WP_003694396.1 CinA family protein -
  E4V86_RS10240 (WHON_01914C) - 1741200..1742048 (-) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  E4V86_RS10245 (WHON_01915C) - 1742142..1743143 (-) 1002 WP_010356039.1 thiamine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44359.71 Da        Isoelectric Point: 4.8123

>NTDB_id=1144229 E4V86_RS10225 WP_047919725.1 1737640..1738893(-) (pilA) [Neisseria gonorrhoeae strain WHO N]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTAGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=1144229 E4V86_RS10225 WP_047919725.1 1737640..1738893(-) (pilA) [Neisseria gonorrhoeae strain WHO N]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTGACCGTGATTTCACAAACTGCGGGCGATTCCGCCGCCGTGTGCTTCGATGCCGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.52

100

0.995

Multiple sequence alignment