Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | E4V86_RS03070 | Genome accession | NZ_LT591910 |
| Coordinates | 522889..523497 (+) | Length | 202 a.a. |
| NCBI ID | WP_047921003.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain WHO N | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 518959..562801 | 522889..523497 | within | 0 |
Gene organization within MGE regions
Location: 518959..562801
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E4V86_RS03050 (WHON_00553) | dnaB | 518959..520365 (+) | 1407 | WP_047951438.1 | replicative DNA helicase | - |
| E4V86_RS03055 (WHON_00554) | pilH | 520673..521338 (+) | 666 | WP_047921008.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| E4V86_RS03060 (WHON_00555) | pilI | 521370..521978 (+) | 609 | WP_047920999.1 | type IV pilus modification protein PilV | Machinery gene |
| E4V86_RS03065 (WHON_00556) | pilJ | 521975..522910 (+) | 936 | WP_047921001.1 | PilW family protein | Machinery gene |
| E4V86_RS03070 (WHON_00557) | pilK | 522889..523497 (+) | 609 | WP_047921003.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| E4V86_RS03075 (WHON_00558) | pilL | 523499..523972 (+) | 474 | WP_172616897.1 | PilX family type IV pilin | Machinery gene |
| E4V86_RS03080 (WHON_00559C) | - | 524042..524350 (-) | 309 | WP_010951048.1 | AzlD family protein | - |
| E4V86_RS03085 | - | 524347..525056 (-) | 710 | Protein_529 | AzlC family ABC transporter permease | - |
| E4V86_RS03090 (WHON_00561) | dut | 525222..525674 (+) | 453 | WP_047951389.1 | dUTP diphosphatase | - |
| E4V86_RS03095 (WHON_00562) | dapC | 525746..526933 (+) | 1188 | WP_003690911.1 | succinyldiaminopimelate transaminase | - |
| E4V86_RS03100 (WHON_00563) | yaaA | 527244..528023 (+) | 780 | WP_003706583.1 | peroxide stress protein YaaA | - |
| E4V86_RS03115 (WHON_00566) | - | 528554..529747 (+) | 1194 | WP_010359935.1 | tyrosine-type recombinase/integrase | - |
| E4V86_RS03125 (WHON_00567C) | - | 530103..530372 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| E4V86_RS03130 (WHON_00568C) | - | 530567..531250 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| E4V86_RS14220 | - | 531531..531797 (-) | 267 | Protein_536 | hypothetical protein | - |
| E4V86_RS03140 (WHON_00570C) | - | 531908..532123 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| E4V86_RS03145 (WHON_00571C) | - | 532175..532666 (-) | 492 | WP_047926688.1 | siphovirus Gp157 family protein | - |
| E4V86_RS03150 (WHON_00572C) | - | 532663..532845 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| E4V86_RS03155 (WHON_00573C) | - | 532985..533671 (-) | 687 | WP_010357532.1 | phage replication initiation protein, NGO0469 family | - |
| E4V86_RS03160 (WHON_00574C) | - | 533740..533901 (-) | 162 | WP_003702497.1 | hypothetical protein | - |
| E4V86_RS03165 (WHON_00575C) | - | 533898..534176 (-) | 279 | WP_144894338.1 | NGO1622 family putative holin | - |
| E4V86_RS03170 (WHON_00576C) | - | 534331..534663 (-) | 333 | WP_003705604.1 | hypothetical protein | - |
| E4V86_RS03175 (WHON_00577C) | - | 534804..535079 (-) | 276 | WP_144894339.1 | hypothetical protein | - |
| E4V86_RS03180 (WHON_00578C) | - | 535076..535552 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| E4V86_RS03185 (WHON_00579C) | - | 535585..535785 (-) | 201 | WP_003687954.1 | hypothetical protein | - |
| E4V86_RS03190 (WHON_00580C) | - | 535983..536396 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| E4V86_RS03195 (WHON_00581C) | - | 536393..536854 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| E4V86_RS03200 (WHON_00582C) | - | 536871..537308 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| E4V86_RS03205 (WHON_00583C) | - | 537423..538139 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| E4V86_RS03210 (WHON_00584) | - | 538214..538444 (+) | 231 | WP_020997318.1 | transcriptional regulator | - |
| E4V86_RS03215 (WHON_00585) | - | 538524..538679 (+) | 156 | WP_047923772.1 | hypothetical protein | - |
| E4V86_RS03220 (WHON_00586C) | - | 538656..538844 (-) | 189 | WP_003698903.1 | hypothetical protein | - |
| E4V86_RS03225 (WHON_00587) | - | 539018..539245 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| E4V86_RS14225 (WHON_00589) | - | 539363..540427 (+) | 1065 | WP_003693470.1 | hypothetical protein | - |
| E4V86_RS03235 (WHON_00590) | - | 540424..541785 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| E4V86_RS03240 (WHON_00591) | - | 541802..542032 (+) | 231 | WP_050154378.1 | hypothetical protein | - |
| E4V86_RS03245 (WHON_00592) | - | 542124..542618 (+) | 495 | WP_144894340.1 | DUF3310 domain-containing protein | - |
| E4V86_RS03250 (WHON_00593) | - | 542795..542944 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| E4V86_RS13630 (WHON_00594) | - | 542972..543253 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| E4V86_RS03255 (WHON_00595) | - | 543244..543681 (+) | 438 | WP_047918627.1 | RusA family crossover junction endodeoxyribonuclease | - |
| E4V86_RS03260 (WHON_00596) | - | 543674..543979 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| E4V86_RS03265 (WHON_00597) | - | 543976..544359 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| E4V86_RS03270 (WHON_00598) | - | 544350..544868 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| E4V86_RS03275 (WHON_00599) | - | 544933..545355 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| E4V86_RS13635 (WHON_00600) | - | 545355..545894 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| E4V86_RS03290 (WHON_00601) | - | 545875..547149 (+) | 1275 | WP_003701186.1 | PBSX family phage terminase large subunit | - |
| E4V86_RS03295 (WHON_00602) | - | 547134..549401 (+) | 2268 | WP_225577699.1 | hypothetical protein | - |
| E4V86_RS03300 (WHON_00603) | - | 549638..550834 (+) | 1197 | WP_003690925.1 | hypothetical protein | - |
| E4V86_RS03305 (WHON_00604) | - | 550831..552045 (+) | 1215 | WP_047954539.1 | hypothetical protein | - |
| E4V86_RS14400 (WHON_00605) | - | 552248..558157 (+) | 5910 | WP_134472138.1 | PLxRFG domain-containing protein | - |
| E4V86_RS03320 (WHON_00607) | - | 558783..560078 (+) | 1296 | WP_003690933.1 | DUF4043 family protein | - |
| E4V86_RS03325 (WHON_00608) | - | 560133..560606 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| E4V86_RS03330 (WHON_00609) | - | 560612..561097 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| E4V86_RS03335 | - | 561094..561369 (+) | 276 | WP_010358526.1 | hypothetical protein | - |
| E4V86_RS03340 (WHON_00610) | - | 561360..561767 (+) | 408 | WP_010358525.1 | hypothetical protein | - |
| E4V86_RS03345 (WHON_00611) | - | 561770..561919 (+) | 150 | WP_003706419.1 | hypothetical protein | - |
| E4V86_RS03350 (WHON_00612C) | - | 561956..562801 (-) | 846 | WP_134472134.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 202 a.a. Molecular weight: 22012.90 Da Isoelectric Point: 7.5809
>NTDB_id=1144206 E4V86_RS03070 WP_047921003.1 522889..523497(+) (pilK) [Neisseria gonorrhoeae strain WHO N]
MRKQNTLTGIPTSDGQRGSALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNGANEETFDNIVVKGKPTVEAVKRSCPAKSGKNSTDLCIDNQGVEYKKGTASVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
MRKQNTLTGIPTSDGQRGSALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNGANEETFDNIVVKGKPTVEAVKRSCPAKSGKNSTDLCIDNQGVEYKKGTASVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
Nucleotide
Download Length: 609 bp
>NTDB_id=1144206 E4V86_RS03070 WP_047921003.1 522889..523497(+) (pilK) [Neisseria gonorrhoeae strain WHO N]
ATGCGCAAACAGAACACTTTGACAGGAATCCCGACTTCTGACGGACAGAGGGGGTCCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACGTTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGGTGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTTCTTGCCCTGCAAAGTCTGGCA
AAAATTCTACCGACCTGTGCATTGACAATCAGGGAGTGGAATATAAGAAAGGGACGGCAAGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
ATGCGCAAACAGAACACTTTGACAGGAATCCCGACTTCTGACGGACAGAGGGGGTCCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACGTTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGGTGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTTCTTGCCCTGCAAAGTCTGGCA
AAAATTCTACCGACCTGTGCATTGACAATCAGGGAGTGGAATATAAGAAAGGGACGGCAAGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
92.611 |
100 |
0.931 |