Detailed information NTG1144127

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: C7R98_RS09700
• Genome accession: NZ_LT591904
• Coordinates: 1643504..1644364 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain WHO M
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1638504..1649364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7R98_RS09680 (WHOM_01802C)	dapD	1639014..1639835 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
C7R98_RS09685 (WHOM_01803C)	pgi	1640045..1641688 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
C7R98_RS09695 (WHOM_01804)	pilG	1642198..1643430 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
C7R98_RS09700 (WHOM_01805)	pilD	1643504..1644364 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
C7R98_RS09705 (WHOM_01806)	coaE	1644361..1644993 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
C7R98_RS09710 (WHOM_01807)	-	1644986..1645195 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
C7R98_RS09715 (WHOM_01808C)	pilF	1645281..1646957 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
C7R98_RS09730 (WHOM_01810C)	-	1647295..1647741 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
C7R98_RS09735 (WHOM_01811C)	-	1647745..1648719 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
C7R98_RS09745 (WHOM_01812)	rplU	1648943..1649251 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=1144127 C7R98_RS09700 WP_003689814.1 1643504..1644364(+) (pilD) [Neisseria gonorrhoeae strain WHO M]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=1144127 C7R98_RS09700 WP_003689814.1 1643504..1644364(+) (pilD) [Neisseria gonorrhoeae strain WHO M]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441