Detailed information NTG1144086

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: C7S00_RS11040
• Genome accession: NZ_LT591901
• Coordinates: 1884082..1884942 (-)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain WHO L
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1879082..1889942

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7S00_RS10995 (WHOL_02054C)	rplU	1879195..1879503 (-)	309	WP_003691838.1	50S ribosomal protein L21	-
C7S00_RS11005 (WHOL_02055)	-	1879727..1880701 (+)	975	WP_010360822.1	polyprenyl synthetase family protein	-
C7S00_RS11010 (WHOL_02056)	-	1880705..1881151 (+)	447	WP_003689818.1	DUF441 domain-containing protein	-
C7S00_RS11025 (WHOL_02058)	pilF	1881489..1883165 (+)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
C7S00_RS11030 (WHOL_02059C)	-	1883251..1883460 (-)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
C7S00_RS11035 (WHOL_02060C)	coaE	1883453..1884085 (-)	633	WP_003689816.1	dephospho-CoA kinase	-
C7S00_RS11040 (WHOL_02061C)	pilD	1884082..1884942 (-)	861	WP_003689814.1	prepilin peptidase	Machinery gene
C7S00_RS11045 (WHOL_02062C)	pilG	1885016..1886248 (-)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
C7S00_RS11055 (WHOL_02063)	pgi	1886758..1888401 (+)	1644	WP_003697594.1	glucose-6-phosphate isomerase	-
C7S00_RS11060 (WHOL_02064)	dapD	1888611..1889432 (+)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=1144086 C7S00_RS11040 WP_003689814.1 1884082..1884942(-) (pilD) [Neisseria gonorrhoeae strain WHO L]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=1144086 C7S00_RS11040 WP_003689814.1 1884082..1884942(-) (pilD) [Neisseria gonorrhoeae strain WHO L]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441