Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   NZAK3_RS02715 Genome accession   NZ_LT009690
Coordinates   561161..561730 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain NZAK3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 556161..566730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NZAK3_RS02690 cysE 557374..558021 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  NZAK3_RS02695 cysS 558005..559405 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  NZAK3_RS02700 - 559398..559802 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  NZAK3_RS02705 rlmB 559810..560556 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  NZAK3_RS02710 - 560556..561080 (+) 525 WP_000664737.1 NYN domain-containing protein -
  NZAK3_RS02715 sigH 561161..561730 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  NZAK3_RS14675 rpmG 561845..561988 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  NZAK3_RS02720 secE 562044..562226 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  NZAK3_RS02725 nusG 562239..562787 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  NZAK3_RS02730 rplK 562968..563390 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  NZAK3_RS02735 rplA 563598..564290 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  NZAK3_RS02740 rplJ 564562..565062 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  NZAK3_RS02745 rplL 565105..565473 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  NZAK3_RS02750 - 565648..566256 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1143562 NZAK3_RS02715 WP_000872882.1 561161..561730(+) (sigH) [Staphylococcus aureus strain NZAK3]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1143562 NZAK3_RS02715 WP_000872882.1 561161..561730(+) (sigH) [Staphylococcus aureus strain NZAK3]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment