Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SSAL8618_RS07355 Genome accession   NZ_CP009913
Coordinates   1624565..1625209 (-) Length   214 a.a.
NCBI ID   WP_022496266.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC 8618     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1619565..1630209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL8618_RS07330 (SSAL8618_07330) - 1621642..1622640 (-) 999 WP_002886866.1 NAD(P)/FAD-dependent oxidoreductase -
  SSAL8618_RS07335 (SSAL8618_07335) trmD 1622642..1623361 (-) 720 WP_002886864.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  SSAL8618_RS07340 (SSAL8618_07340) rimM 1623351..1623869 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  SSAL8618_RS07355 (SSAL8618_07355) vraR 1624565..1625209 (-) 645 WP_022496266.1 response regulator transcription factor Regulator
  SSAL8618_RS07360 (SSAL8618_07360) - 1625199..1626209 (-) 1011 WP_038676486.1 sensor histidine kinase -
  SSAL8618_RS07365 (SSAL8618_07365) liaF 1626206..1626904 (-) 699 WP_038676488.1 cell wall-active antibiotics response protein LiaF -
  SSAL8618_RS07370 (SSAL8618_07370) - 1627068..1627826 (-) 759 WP_038676489.1 potassium channel family protein -
  SSAL8618_RS07375 (SSAL8618_07375) stkP/pknB 1627974..1629848 (-) 1875 WP_038676492.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23991.33 Da        Isoelectric Point: 4.5814

>NTDB_id=114352 SSAL8618_RS07355 WP_022496266.1 1624565..1625209(-) (vraR) [Streptococcus salivarius strain NCTC 8618]
MSNKINVILVDDHEMVRLGLKSFLNLQGDIEVVGEAGNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=114352 SSAL8618_RS07355 WP_022496266.1 1624565..1625209(-) (vraR) [Streptococcus salivarius strain NCTC 8618]
ATGTCGAATAAGATTAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATATAGAAGTAGTTGGAGAGGCAGGGAATGGTCGAGAGGGTGTCGATCTTGCCTTGGAACTGCGTCCGGATGTCG
TCGTTATGGATCTTGTCATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCGGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTACCCAGTCATTGAAGCTGGTGCTAAAGGCTATATGCTTAA
AACTAGTAGTGCGGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCATGATAGTCATCCGGACTTACACGATGACTTGACGGCACGTGAACGTGATATCTTGGCCCTTTTG
GCTAAGGGGTATGACAATCAAACCATTGCTAATGAGCTATTTATTTCGTTGAAAACCGTTAAAACTCACGTGTCTAATAT
CCTTGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTTGTTTATGCCTTTAGACATCATTTGGTTTCGCAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.971

96.262

0.491
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379