Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQL00_RS06375 Genome accession   NZ_LS483523
Coordinates   1181086..1182318 (+) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1176086..1187318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS06345 - 1176157..1176834 (+) 678 WP_000221611.1 DnaD domain-containing protein -
  DQL00_RS06350 tpiA 1176932..1177690 (+) 759 WP_000087897.1 triose-phosphate isomerase -
  DQL00_RS06355 lytC 1177728..1179233 (+) 1506 WP_075575672.1 choline binding-anchored murein hydrolase LytC -
  DQL00_RS06360 - 1179730..1180248 (+) 519 WP_000229874.1 Dps family protein -
  DQL00_RS06365 - 1180378..1180884 (+) 507 WP_069286974.1 dihydrofolate reductase -
  DQL00_RS06370 - 1180884..1181054 (+) 171 WP_000442276.1 hypothetical protein -
  DQL00_RS06375 clpX 1181086..1182318 (+) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQL00_RS06380 yihA 1182327..1182914 (+) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQL00_RS06385 - 1182925..1183305 (+) 381 WP_001140413.1 RidA family protein -
  DQL00_RS06390 rapZ 1183357..1184247 (+) 891 WP_000163033.1 RNase adapter RapZ -
  DQL00_RS06395 - 1184244..1185221 (+) 978 WP_001231086.1 YvcK family protein -
  DQL00_RS06400 whiA 1185218..1186129 (+) 912 WP_000011310.1 DNA-binding protein WhiA -
  DQL00_RS06405 - 1186163..1187128 (-) 966 WP_000081011.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=1142972 DQL00_RS06375 WP_000106346.1 1181086..1182318(+) (clpX) [Streptococcus pneumoniae strain 4041STDY6836169]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1142972 DQL00_RS06375 WP_000106346.1 1181086..1182318(+) (clpX) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
CGCTGGTAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCAGAAGTTCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTTATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAATCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGTCCAACTGGTTCAGGGAAAACATTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCGATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTTAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment