Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQL00_RS00675 Genome accession   NZ_LS483523
Coordinates   135808..136497 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 130808..141497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS12170 - 131480..131809 (-) 330 WP_000196978.1 transposase -
  DQL00_RS11785 - 132472..132810 (+) 339 Protein_124 lantibiotic-modifying protein -
  DQL00_RS00660 - 132710..133297 (+) 588 WP_001835194.1 lanthionine synthetase LanC family protein -
  DQL00_RS00665 - 133340..134572 (+) 1233 WP_000765673.1 MFS transporter -
  DQL00_RS00670 cbpC 134690..135709 (-) 1020 WP_023396153.1 choline-binding protein CbpC -
  DQL00_RS00675 covR 135808..136497 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  DQL00_RS00680 gndA 136509..137933 (-) 1425 WP_023396152.1 NADP-dependent phosphogluconate dehydrogenase -
  DQL00_RS00685 mapZ 138009..139403 (-) 1395 WP_023396578.1 cell division site-positioning protein MapZ -
  DQL00_RS00690 - 139416..140573 (-) 1158 WP_000711393.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  DQL00_RS00700 gpsB 141059..141388 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=1142918 DQL00_RS00675 WP_000518011.1 135808..136497(-) (covR) [Streptococcus pneumoniae strain 4041STDY6836169]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1142918 DQL00_RS00675 WP_000518011.1 135808..136497(-) (covR) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment