Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   DQN84_RS14450 Genome accession   NZ_LS483476
Coordinates   2962179..2963999 (-) Length   606 a.a.
NCBI ID   WP_066140507.1    Uniprot ID   A0A2X4WTB5
Organism   Lederbergia lenta strain NCTC4824     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2957179..2968999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN84_RS14415 (NCTC4824_02967) - 2957212..2958012 (-) 801 WP_066140490.1 NAD kinase -
  DQN84_RS14420 (NCTC4824_02968) - 2958052..2958699 (-) 648 WP_066140493.1 GTP pyrophosphokinase -
  DQN84_RS14425 (NCTC4824_02969) - 2958876..2959472 (+) 597 WP_066140495.1 CYTH domain-containing protein -
  DQN84_RS14430 (NCTC4824_02970) - 2959504..2960184 (+) 681 WP_066140497.1 lytic transglycosylase domain-containing protein -
  DQN84_RS14435 (NCTC4824_02971) - 2960317..2960718 (+) 402 WP_066140500.1 globin -
  DQN84_RS14440 (NCTC4824_02972) - 2960718..2961584 (+) 867 WP_066140504.1 ClpXP adapter SpxH family protein -
  DQN84_RS14450 (NCTC4824_02973) pepF 2962179..2963999 (-) 1821 WP_066140507.1 oligoendopeptidase F Regulator
  DQN84_RS14455 (NCTC4824_02974) - 2964084..2965328 (-) 1245 WP_066140510.1 competence protein CoiA -
  DQN84_RS14460 (NCTC4824_02975) mecA 2965403..2966059 (-) 657 WP_066140513.1 adaptor protein MecA -
  DQN84_RS14465 (NCTC4824_02976) spxA 2966565..2966960 (-) 396 WP_066140516.1 transcriptional regulator SpxA -
  DQN84_RS14470 (NCTC4824_02977) - 2967349..2968554 (-) 1206 WP_420812698.1 putative glycoside hydrolase -

Sequence

Protein


Download         Length: 606 a.a.        Molecular weight: 69678.98 Da        Isoelectric Point: 4.6714

>NTDB_id=1142449 DQN84_RS14450 WP_066140507.1 2962179..2963999(-) (pepF) [Lederbergia lenta strain NCTC4824]
MTNNTNVKTLPARSEIAEELTWKLEDIFATDELWEKEYEGIKDSLNQATQYRGQLHESSDKLFEVLQYQSHVSERMGKLY
TYAHMRYDQDTGNAHYQGLNARAESLYSQVASAFSYVVPEILAMDEREIAQFLTENKELQLYRQVLEEINLQRGHVLSAE
QEAMLAEASEVLSSSSTTFGMLNNADMEFPVMKDENGEEVQISHGNYIRFLESQDRRVRKEAFEKVYETYGKYKNTLSST
LGGAVKKDNFYAKTRNYSSARAAALAANNIPETVYDTLVETINKNLHLLQRYVKLRKKLLGVDKLHMYDLYTPLIQDVEM
EISYDEAKELMVNGLAPLGEDYIHTIKEGLDNRWVDVVENKGKRSGAYSSGTYGTNPYILMNWQDNVNNLFTLAHEFGHS
AHSYYTRKSQPYPYGNYSIFVAEVASTCNEALLGDYLLNETEDKQKRLYLINNYLEGFRGTVFRQTMFAEFEHLIHQKAQ
QGEALTADLLTKEYYALNKKYFGEEDIHIDEEIGLEWSRIPHFYYNYYVYQYATGFSAAAALSKQILEEGEPAVERYLDF
LKAGSSDYPIEVLKKAGVDMTTAEPIEAACKVFEAKLDEMEQLLSE

Nucleotide


Download         Length: 1821 bp        

>NTDB_id=1142449 DQN84_RS14450 WP_066140507.1 2962179..2963999(-) (pepF) [Lederbergia lenta strain NCTC4824]
ATGACAAATAATACAAATGTAAAAACATTACCAGCTAGATCGGAGATCGCAGAGGAATTAACTTGGAAATTAGAGGATAT
CTTCGCAACAGATGAATTATGGGAAAAAGAATATGAAGGTATAAAAGATAGTTTAAATCAAGCAACCCAATATAGGGGGC
AATTACATGAAAGTTCAGATAAATTATTTGAAGTATTGCAATATCAATCTCATGTGTCTGAACGAATGGGTAAGTTATAT
ACATACGCACATATGCGCTATGACCAAGATACAGGGAACGCTCATTATCAGGGGTTAAATGCGCGTGCCGAAAGTTTATA
TTCGCAAGTTGCAAGTGCATTTTCTTATGTAGTGCCCGAGATATTAGCAATGGATGAAAGGGAAATAGCTCAATTTTTAA
CAGAGAATAAAGAACTTCAGCTTTATCGTCAAGTGTTAGAGGAAATCAATCTTCAACGTGGTCATGTTTTATCAGCTGAA
CAAGAAGCGATGCTTGCGGAAGCCTCAGAGGTGCTAAGCTCGTCTAGTACAACATTTGGTATGCTTAATAACGCGGATAT
GGAGTTTCCAGTAATGAAAGATGAGAATGGCGAAGAAGTTCAAATTTCTCACGGTAATTATATTCGCTTTCTTGAAAGCC
AAGATCGCAGAGTACGGAAAGAGGCATTTGAAAAAGTATATGAAACTTATGGGAAATATAAAAATACACTTTCTAGCACA
TTAGGTGGTGCAGTAAAAAAAGATAACTTTTATGCGAAAACAAGAAATTATTCTTCAGCCAGAGCAGCTGCACTTGCAGC
TAACAATATACCAGAGACAGTTTATGATACACTTGTGGAAACAATTAATAAAAACTTACATTTATTGCAGCGTTACGTAA
AGTTACGTAAAAAATTACTGGGCGTTGATAAACTTCATATGTATGACCTTTATACGCCATTAATTCAAGATGTAGAAATG
GAAATATCATATGATGAAGCGAAGGAATTAATGGTTAATGGATTAGCTCCTTTAGGAGAAGATTATATTCATACGATTAA
GGAAGGCTTAGATAATCGTTGGGTAGATGTTGTTGAAAACAAAGGGAAACGAAGCGGTGCATATTCTTCAGGTACATATG
GAACAAATCCATATATATTAATGAACTGGCAGGATAATGTAAATAATCTATTTACACTGGCACATGAATTTGGCCATAGT
GCTCATAGTTATTACACTAGAAAATCTCAGCCATATCCGTATGGCAACTATTCTATTTTCGTGGCTGAAGTAGCTTCGAC
ATGTAATGAGGCATTATTAGGTGATTATCTGTTGAATGAAACGGAAGACAAGCAAAAGAGATTATATTTAATCAATAATT
ATTTAGAAGGCTTTAGGGGAACTGTATTTAGACAGACGATGTTTGCTGAGTTTGAACATTTAATCCATCAAAAGGCCCAG
CAAGGAGAAGCATTGACTGCCGATCTACTAACGAAAGAATACTATGCATTAAATAAAAAATATTTTGGAGAAGAAGATAT
TCATATTGATGAAGAAATTGGTCTTGAATGGTCGAGGATTCCCCATTTTTATTATAATTATTATGTGTATCAGTATGCTA
CGGGCTTTAGTGCAGCAGCGGCACTTTCTAAGCAAATACTTGAAGAAGGGGAGCCTGCTGTAGAACGTTACTTGGACTTC
CTAAAAGCTGGAAGCTCTGATTACCCTATTGAAGTGCTGAAAAAAGCTGGAGTCGATATGACTACGGCAGAGCCAATTGA
GGCAGCTTGTAAAGTATTTGAAGCAAAGCTAGATGAAATGGAACAATTATTATCAGAGTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(211-590)

Oligopeptidase F (Peptidase_M3_N)

(120-189)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X4WTB5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

49.663

98.02

0.487

Multiple sequence alignment