Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQN71_RS08420 Genome accession   NZ_LS483471
Coordinates   1605067..1605756 (-) Length   229 a.a.
NCBI ID   WP_015605580.1    Uniprot ID   A0A512AD48
Organism   Streptococcus cristatus strain NCTC13807     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1600067..1610756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN71_RS08395 (NCTC13807_01610) - 1601074..1601793 (-) 720 WP_015605576.1 DUF4176 domain-containing protein -
  DQN71_RS08400 (NCTC13807_01611) - 1601793..1602092 (-) 300 WP_015605577.1 hypothetical protein -
  DQN71_RS08405 (NCTC13807_01612) - 1602104..1602532 (-) 429 WP_015605578.1 hypothetical protein -
  DQN71_RS08410 (NCTC13807_01613) - 1602598..1604211 (-) 1614 WP_015605579.1 ribonuclease Y -
  DQN71_RS08415 (NCTC13807_01614) - 1604489..1604971 (+) 483 WP_005590897.1 S-ribosylhomocysteine lyase -
  DQN71_RS08420 (NCTC13807_01615) covR 1605067..1605756 (-) 690 WP_015605580.1 DNA-binding response regulator Regulator
  DQN71_RS08425 (NCTC13807_01616) gndA 1605766..1607190 (-) 1425 WP_015605581.1 NADP-dependent phosphogluconate dehydrogenase -
  DQN71_RS08430 (NCTC13807_01617) - 1607353..1608816 (-) 1464 WP_015605582.1 flotillin family protein -
  DQN71_RS08435 (NCTC13807_01618) - 1608997..1609680 (-) 684 WP_015605583.1 Bax inhibitor-1/YccA family protein -
  DQN71_RS08440 (NCTC13807_01619) - 1609700..1610191 (-) 492 WP_041826827.1 HDIG domain-containing metalloprotein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26528.62 Da        Isoelectric Point: 6.2792

>NTDB_id=1142329 DQN71_RS08420 WP_015605580.1 1605067..1605756(-) (covR) [Streptococcus cristatus strain NCTC13807]
MAKRILLVENEKNLARFVTLELQKEAYLLDVVETGSQGLALARENDYDLLLLNYDLQDMTASEFAKQLSLLKPASVIIVL
ASREEIKEHVDEIQRFAVSYTIKPFIISDLVEKVSDIFRGRDFIDQHCSKLKTPTAYRNLRVDLKNHIVYRGEEVIALTR
REYDLLVTLMSNQKVMSREQLLERVWKYEGATETNVVDVYIRYLRSKIDIAGQTSYIKTVRGIGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1142329 DQN71_RS08420 WP_015605580.1 1605067..1605756(-) (covR) [Streptococcus cristatus strain NCTC13807]
ATGGCAAAGCGAATTTTATTAGTAGAAAATGAAAAGAATCTTGCACGATTTGTGACTTTGGAACTGCAAAAGGAAGCTTA
TCTTCTGGATGTAGTTGAGACAGGAAGTCAAGGTTTGGCGTTGGCCAGAGAAAATGACTACGATCTGCTCTTGCTTAATT
ATGACTTGCAGGATATGACTGCTAGTGAGTTTGCCAAGCAACTGAGCTTGCTCAAACCGGCTTCGGTTATTATCGTCTTA
GCTAGCCGTGAAGAAATCAAAGAACATGTAGATGAGATTCAGCGCTTTGCAGTCTCCTATACCATAAAGCCTTTTATTAT
CAGTGATTTGGTTGAGAAAGTCTCCGATATTTTTCGAGGTCGGGACTTTATCGACCAGCATTGTAGCAAGCTGAAAACAC
CGACTGCTTACCGCAATCTACGAGTTGATTTGAAAAATCATATCGTCTATCGTGGAGAGGAAGTGATTGCCTTGACACGA
CGGGAATATGATCTGCTGGTGACGCTGATGAGCAACCAAAAGGTCATGAGCCGCGAGCAGCTTCTGGAACGTGTCTGGAA
GTATGAAGGCGCCACTGAGACCAACGTAGTCGATGTCTATATTCGCTATCTACGTAGTAAGATTGATATTGCTGGTCAGA
CTAGCTATATCAAAACTGTCCGTGGCATTGGCTATGCTATGCAGGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A512AD48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

47.162

100

0.472

Multiple sequence alignment