Detailed information NTG1142085

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQL01_RS10145
• Genome accession: NZ_LS483451
• Coordinates: 1894217..1895254 (-)
• Length: 345 a.a.
• NCBI ID: WP_061368781.1
• Uniprot ID: A0AAQ3A0K8
• Organism: Streptococcus pneumoniae strain 4041STDY6836166
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1889217..1900254

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL01_RS10120	endA	1889835..1890659 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
DQL01_RS10125	-	1891016..1892269 (+)	1254	WP_061368780.1	IS110-like element ISSpn10 family transposase	-
DQL01_RS10130	-	1892441..1892629 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
DQL01_RS10135	murA	1892622..1893905 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQL01_RS10140	-	1893929..1894159 (-)	231	WP_000250393.1	DUF1146 family protein	-
DQL01_RS10145	sepM	1894217..1895254 (-)	1038	WP_061368781.1	SepM family pheromone-processing serine protease	Regulator
DQL01_RS10150	coaD	1895238..1895726 (-)	489	WP_111702722.1	pantetheine-phosphate adenylyltransferase	-
DQL01_RS10155	rsmD	1895716..1896255 (-)	540	WP_050965571.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQL01_RS10160	asnA	1896320..1897312 (-)	993	WP_050965570.1	aspartate--ammonia ligase	-
DQL01_RS10170	-	1897424..1898107 (-)	684	WP_050965569.1	Bax inhibitor-1 family protein	-
DQL01_RS10175	-	1898163..1898903 (-)	741	WP_111702723.1	TrmH family RNA methyltransferase	-
DQL01_RS10180	-	1898937..1899215 (+)	279	WP_050314492.1	acylphosphatase	-
DQL01_RS10185	yidC	1899293..1900219 (+)	927	WP_111702724.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37542.55 Da
• Isoelectric Point: 4.9480

>NTDB_id=1142085 DQL01_RS10145 WP_061368781.1 1894217..1895254(-) (sepM) [Streptococcus pneumoniae strain 4041STDY6836166]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMARYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIANPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1142085 DQL01_RS10145 WP_061368781.1 1894217..1895254(-) (sepM) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGAAAAAAAAGATTAGATGGCCCTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAGGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGGAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTAACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591