Detailed information NTG1141994

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: DQL12_RS09620
• Genome accession: NZ_LS483450
• Coordinates: 1789953..1791020 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain 4041STDY6583227
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1784953..1796020

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL12_RS09595	treR	1785130..1785840 (+)	711	WP_050255457.1	trehalose operon repressor	Regulator
DQL12_RS09600	-	1785873..1786676 (-)	804	WP_000157674.1	ABC transporter ATP-binding protein	-
DQL12_RS09605	-	1786689..1787566 (-)	878	Protein_1807	ABC transporter permease	-
DQL12_RS09610	-	1787578..1788387 (-)	810	Protein_1808	ABC transporter substrate-binding protein	-
DQL12_RS09615	amiF	1789016..1789942 (-)	927	WP_001291296.1	ATP-binding cassette domain-containing protein	Regulator
DQL12_RS09620	amiE	1789953..1791020 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
DQL12_RS09625	amiD	1791029..1791955 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
DQL12_RS09630	amiC	1791955..1793451 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
DQL12_RS09635	amiA3	1793518..1795497 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=1141994 DQL12_RS09620 WP_000159554.1 1789953..1791020(-) (amiE) [Streptococcus pneumoniae strain 4041STDY6583227]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=1141994 DQL12_RS09620 WP_000159554.1 1789953..1791020(-) (amiE) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541