Detailed information NTG1141986

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQL12_RS08120
• Genome accession: NZ_LS483450
• Coordinates: 1519586..1520818 (-)
• Length: 410 a.a.
• NCBI ID: WP_000106346.1
• Uniprot ID: A0A064C077
• Organism: Streptococcus pneumoniae strain 4041STDY6583227
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1514586..1525818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL12_RS08090	-	1514773..1515741 (+)	969	WP_000081000.1	NAD(P)/FAD-dependent oxidoreductase	-
DQL12_RS08095	whiA	1515775..1516686 (-)	912	WP_000011306.1	DNA-binding protein WhiA	-
DQL12_RS08100	-	1516683..1517660 (-)	978	WP_001231089.1	YvcK family protein	-
DQL12_RS08105	rapZ	1517657..1518547 (-)	891	WP_000163035.1	RNase adapter RapZ	-
DQL12_RS08110	-	1518599..1518979 (-)	381	WP_001140412.1	RidA family protein	-
DQL12_RS08115	yihA	1518990..1519577 (-)	588	WP_000422599.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQL12_RS08120	clpX	1519586..1520818 (-)	1233	WP_000106346.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQL12_RS08130	-	1521020..1521526 (-)	507	WP_050972239.1	dihydrofolate reductase	-
DQL12_RS08135	-	1521656..1522174 (-)	519	WP_000229874.1	Dps family protein	-
DQL12_RS08145	-	1522683..1524029 (+)	1347	WP_001808790.1	IS1380-like element ISSpn5 family transposase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45798.35 Da
• Isoelectric Point: 4.4550

>NTDB_id=1141986 DQL12_RS08120 WP_000106346.1 1519586..1520818(-) (clpX) [Streptococcus pneumoniae strain 4041STDY6583227]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=1141986 DQL12_RS08120 WP_000106346.1 1519586..1520818(-) (clpX) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATACTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATATATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

3D structure

• AlphaFold DB: A0A064C077

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	86.585	100	0.866
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.214	98.049	0.561