Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQL12_RS01960 Genome accession   NZ_LS483450
Coordinates   361440..362129 (+) Length   229 a.a.
NCBI ID   WP_000518017.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 356440..367129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS01935 gpsB 356549..356878 (+) 330 WP_000146522.1 cell division regulator GpsB -
  DQL12_RS01945 - 357364..358521 (+) 1158 WP_000711385.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  DQL12_RS01950 mapZ 358534..359928 (+) 1395 WP_050255498.1 cell division site-positioning protein MapZ -
  DQL12_RS01955 gndA 360004..361428 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  DQL12_RS01960 covR 361440..362129 (+) 690 WP_000518017.1 response regulator transcription factor Regulator
  DQL12_RS01965 cbpC 362227..363252 (+) 1026 WP_050255497.1 choline-binding protein CbpC -
  DQL12_RS01970 cbpJ 363271..364269 (+) 999 WP_050255496.1 choline-binding protein CbpJ -
  DQL12_RS01975 - 364387..365619 (-) 1233 WP_000765674.1 MFS transporter -
  DQL12_RS01980 - 365662..366081 (-) 420 WP_000499616.1 hypothetical protein -
  DQL12_RS01985 - 366149..366537 (-) 389 Protein_369 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26893.19 Da        Isoelectric Point: 6.9836

>NTDB_id=1141962 DQL12_RS01960 WP_000518017.1 361440..362129(+) (covR) [Streptococcus pneumoniae strain 4041STDY6583227]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRNYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1141962 DQL12_RS01960 WP_000518017.1 361440..362129(+) (covR) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATTTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGAACTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

100

0.463

Multiple sequence alignment