Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQK98_RS01995 Genome accession   NZ_LS483449
Coordinates   373753..374442 (+) Length   229 a.a.
NCBI ID   WP_050198358.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836170     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 368753..379442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK98_RS01970 gpsB 368886..369215 (+) 330 WP_000146522.1 cell division regulator GpsB -
  DQK98_RS01980 - 369701..370858 (+) 1158 WP_050198360.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  DQK98_RS01985 mapZ 370871..372241 (+) 1371 WP_050198359.1 cell division site-positioning protein MapZ -
  DQK98_RS01990 gndA 372317..373741 (+) 1425 WP_111688029.1 NADP-dependent phosphogluconate dehydrogenase -
  DQK98_RS01995 covR 373753..374442 (+) 690 WP_050198358.1 response regulator transcription factor Regulator
  DQK98_RS02000 cbpC 374541..375560 (+) 1020 WP_111688030.1 choline-binding protein CbpC -
  DQK98_RS02005 - 375678..376910 (-) 1233 WP_050089970.1 MFS transporter -
  DQK98_RS02010 - 376953..377828 (-) 876 WP_230401509.1 lanthionine synthetase LanC family protein -
  DQK98_RS12085 - 378440..378769 (+) 330 WP_000196981.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=1141885 DQK98_RS01995 WP_050198358.1 373753..374442(+) (covR) [Streptococcus pneumoniae strain 4041STDY6836170]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1141885 DQK98_RS01995 WP_050198358.1 373753..374442(+) (covR) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.652

100

0.459

Multiple sequence alignment