Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DQN48_RS03690 Genome accession   NZ_LS483446
Coordinates   785296..787089 (-) Length   597 a.a.
NCBI ID   WP_013023020.1    Uniprot ID   D3UHG9
Organism   Helicobacter mustelae strain NCTC12198     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 780296..792089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN48_RS03655 (NCTC12198_00704) - 780607..781062 (-) 456 WP_231902627.1 YhcH/YjgK/YiaL family protein -
  DQN48_RS03660 (NCTC12198_00705) ribA 781195..781776 (+) 582 WP_013023014.1 GTP cyclohydrolase II -
  DQN48_RS03665 (NCTC12198_00706) - 781786..783018 (+) 1233 WP_013023015.1 molybdopterin molybdotransferase MoeA -
  DQN48_RS03670 (NCTC12198_00707) - 783015..783236 (+) 222 WP_013023016.1 MoaD/ThiS family protein -
  DQN48_RS03675 (NCTC12198_00708) - 783240..783677 (+) 438 WP_013023017.1 molybdenum cofactor biosynthesis protein MoaE -
  DQN48_RS03680 (NCTC12198_00710) mog 783732..784259 (+) 528 WP_013023018.1 molybdopterin adenylyltransferase -
  DQN48_RS03685 (NCTC12198_00711) moaC 784272..784745 (+) 474 WP_013023019.1 cyclic pyranopterin monophosphate synthase MoaC -
  DQN48_RS03690 (NCTC12198_00712) uvrC 785296..787089 (-) 1794 WP_013023020.1 excinuclease ABC subunit UvrC Machinery gene
  DQN48_RS03695 (NCTC12198_00713) - 787083..787535 (-) 453 WP_013023021.1 hypothetical protein -
  DQN48_RS03700 (NCTC12198_00714) - 787643..789682 (+) 2040 WP_013023022.1 FUSC family protein -
  DQN48_RS03705 (NCTC12198_00715) - 789683..790384 (+) 702 WP_013023023.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 597 a.a.        Molecular weight: 68918.97 Da        Isoelectric Point: 10.1053

>NTDB_id=1141789 DQN48_RS03690 WP_013023020.1 785296..787089(-) (uvrC) [Helicobacter mustelae strain NCTC12198]
MLDPKILQNLPTTFGVYQYFDANGKLLYVGKAKNIKKRVKSYFRIFENTLIPNPTASTRIKLMLSQVSHIHTMVVSSEQD
ALLLENSMIKQLKPKYNILLRDDKTYPYIVIDLEEDFPSISITRKIQDQKSLRYFGPYPSGGRDILDSLQDLLPLVQKKS
CVKGKKACLFYQIQKCPAPCENKISKDAYALTIKQAIKILQNKKLLLSLIEQKMLSLSQNLLFEEAQIYKNRLQKIKELS
SFSEISAQKPYDLDIISAIKEPHKNGYIAILVKLFMRNGKIIAADSKRVRSDYDIDIQSLFTQYLLSHYKHKLPLLPQAI
LVSEELEDVQGLQNFLQDTQGRKIPISVPKSGFKKNLIHIGIKNARELLRQEANLCASDILIQIKESFALSQTPFRIEVF
DTSHHAMSFNVGGMIVYDMQNFDPSSYRHYNLQSKDEYAQMREMLLHRIESFVKSPPPNLWVIDGGRAQLNLAQNLLESA
GYDIDILAISKEKRDHKAYRAKGYARDRIYTKERDLRLDPSDKRLQFLQKLRDESHRFAIKFHRSQKTKNLTKNLPYTTA
EQKRLLQYFGDFAKLQSASAQEISQVLRNKPSKKTQG

Nucleotide


Download         Length: 1794 bp        

>NTDB_id=1141789 DQN48_RS03690 WP_013023020.1 785296..787089(-) (uvrC) [Helicobacter mustelae strain NCTC12198]
ATGCTAGATCCCAAAATCCTGCAAAATCTCCCCACCACCTTTGGGGTCTATCAGTATTTTGATGCCAATGGCAAGCTACT
GTATGTAGGCAAGGCAAAAAATATCAAAAAACGCGTGAAGAGCTATTTTCGCATTTTTGAAAACACCCTCATCCCCAATC
CCACCGCAAGCACGCGCATCAAGCTCATGCTCTCCCAAGTCTCACACATCCATACCATGGTGGTATCTAGCGAGCAAGAC
GCACTGCTCTTAGAAAATTCCATGATTAAACAGCTCAAACCCAAATACAATATTCTCCTTCGCGATGACAAAACCTATCC
CTACATTGTCATAGATCTTGAGGAAGATTTCCCCAGCATCTCCATCACGCGCAAGATCCAAGATCAAAAATCCCTGCGCT
ATTTTGGCCCCTATCCCAGCGGTGGGCGCGATATTTTGGACAGTCTGCAGGATCTCCTGCCTCTGGTACAAAAAAAATCC
TGTGTCAAGGGCAAAAAAGCCTGTCTTTTTTATCAGATCCAAAAATGCCCAGCCCCTTGTGAAAATAAAATCAGCAAAGA
TGCCTACGCGCTGACTATCAAGCAGGCCATAAAGATACTGCAAAACAAAAAACTCCTACTGTCTTTAATCGAGCAAAAAA
TGCTTTCTTTGTCACAAAATCTCCTCTTTGAAGAAGCCCAGATTTACAAAAACCGCCTGCAAAAAATCAAAGAATTAAGC
AGCTTTTCTGAGATTTCTGCCCAAAAGCCCTATGATCTTGACATCATTAGCGCAATCAAAGAGCCACACAAAAATGGCTA
CATCGCGATCCTAGTGAAGCTTTTCATGCGCAATGGCAAAATCATCGCCGCAGATTCCAAGCGTGTGCGCAGTGATTATG
ACATTGATATCCAATCCCTCTTCACCCAATACCTACTCTCGCATTACAAACACAAGCTCCCCCTACTCCCGCAAGCAATT
TTAGTCTCTGAAGAGCTAGAAGATGTGCAGGGTTTGCAAAATTTCCTCCAAGATACCCAGGGCAGAAAAATCCCTATCTC
CGTGCCAAAATCAGGCTTCAAAAAAAATCTCATTCACATTGGCATCAAAAATGCAAGAGAGCTCCTACGCCAGGAGGCAA
ATCTCTGTGCTAGCGATATTCTCATCCAAATCAAAGAATCCTTTGCTCTCTCTCAAACTCCCTTTCGCATCGAGGTTTTT
GACACGAGTCATCATGCCATGAGCTTCAATGTAGGGGGCATGATCGTCTATGACATGCAAAATTTTGACCCCTCCTCCTA
TCGGCACTACAATCTCCAATCCAAAGATGAATACGCCCAAATGCGTGAAATGCTCCTACATCGCATTGAGAGCTTTGTCA
AATCACCCCCGCCCAATCTCTGGGTCATTGATGGAGGCAGAGCGCAATTGAATCTAGCTCAAAATCTCCTAGAGAGTGCA
GGATATGACATCGATATCCTAGCCATCTCCAAAGAAAAAAGAGACCACAAGGCTTATCGCGCCAAGGGATATGCAAGGGA
TAGGATTTATACCAAAGAAAGGGATTTGAGGCTTGATCCCAGTGATAAGAGGCTGCAATTTTTGCAAAAACTGCGCGATG
AATCCCACCGTTTTGCTATAAAATTCCATCGCAGTCAAAAGACCAAAAATCTCACCAAAAATCTACCCTACACCACCGCA
GAACAAAAGCGACTTTTGCAATATTTTGGAGACTTTGCCAAACTCCAATCTGCCAGCGCGCAAGAAATCTCCCAAGTACT
AAGAAACAAACCCAGCAAAAAAACCCAAGGCTAG

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(386-540)

GIY-YIG catalytic domain (GIY-YIG)

(14-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3UHG9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.695

98.827

0.511

Multiple sequence alignment