Detailed information NTG1141748

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQL20_RS05555
• Genome accession: NZ_LS483444
• Coordinates: 1034976..1036208 (-)
• Length: 410 a.a.
• NCBI ID: WP_006596312.1
• Uniprot ID: E7SB47
• Organism: Streptococcus australis strain NCTC13166
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1029976..1041208

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL20_RS05520 (NCTC11371_01081)	-	1030385..1030837 (-)	453	WP_006596317.1	hypothetical protein	-
DQL20_RS05525 (NCTC11371_01082)	rplL	1031354..1031722 (-)	369	WP_001196965.1	50S ribosomal protein L7/L12	-
DQL20_RS05530 (NCTC11371_01083)	rplJ	1031799..1032299 (-)	501	WP_006596316.1	50S ribosomal protein L10	-
DQL20_RS05540 (NCTC11371_01085)	-	1032535..1033332 (-)	798	WP_006597355.1	formate/nitrite transporter family protein	-
DQL20_RS05545 (NCTC11371_01086)	-	1033523..1034221 (-)	699	WP_006596314.1	glucosaminidase domain-containing protein	-
DQL20_RS05550 (NCTC11371_01087)	yihA	1034368..1034964 (-)	597	WP_006596313.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQL20_RS05555 (NCTC11371_01088)	clpX	1034976..1036208 (-)	1233	WP_006596312.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQL20_RS05565 (NCTC11371_01090)	-	1036419..1036931 (-)	513	WP_006596310.1	dihydrofolate reductase	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45523.00 Da
• Isoelectric Point: 4.3719

>NTDB_id=1141748 DQL20_RS05555 WP_006596312.1 1034976..1036208(-) (clpX) [Streptococcus australis strain NCTC13166]
MPTNQSNDMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHENREDDNDVDLQKSNILMVGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGKNNKAIDESSSYMQEIIAEDIQKFGIIPELIGRLPVLAALEQLTVDDLVR
ILKEPRNALVKQYQALLSFDDVELEFDDEALEEIASKAIERKTGARGLRSIIEETMLDVMFEVPSQEDVKLVRITKEAVN
GTEKPILETA

Nucleotide

• Length: 1233 bp

>NTDB_id=1141748 DQL20_RS05555 WP_006596312.1 1034976..1036208(-) (clpX) [Streptococcus australis strain NCTC13166]
ATGCCTACAAATCAATCAAACGATATGATGGTTTATTGTTCGTTTTGTGGTAAGAACCAAGACGAAGTACAGAAGATTAT
TGCTGGGAACAATGCCTTTATCTGTAATGAATGTGTTGAGTTAGCTCAAGAAATCATTCGAGAAGAATTAGCTGAGGAAG
TCTTGGCAGACCTTTCAGAGGTTCCAAAACCAATCGAACTTCTCAATATCCTTAACCACTATGTCATCGGTCAAGATCGT
GCTAAACGAGCACTAGCAGTAGCTGTCTACAATCACTACAAACGGATTAACTTCCACGAAAATCGTGAAGATGACAATGA
TGTGGATTTACAAAAATCAAACATTTTGATGGTCGGTCCTACAGGTTCAGGAAAAACTTTCTTGGCTCAAACGCTTGCTA
AGAGCTTGAATGTTCCATTTGCCATCGCCGATGCCACAGCCTTGACAGAAGCGGGTTACGTCGGAGAAGACGTTGAAAAC
ATCCTTCTTAAGCTCTTGCAAGCGGCTGACTTCAATATTGAACGTGCAGAACGTGGCATCATCTATGTTGATGAAATCGA
TAAGATTGCTAAGAAGAGCGAGAACGTCTCGATCACTCGTGATGTATCTGGTGAAGGGGTACAGCAAGCCCTCTTGAAGA
TCATCGAGGGTACTGTAGCGAGTGTTCCACCTCAAGGCGGACGCAAGCATCCTCAACAAGAGATGATCCAAGTTGACACC
AAAAACATTCTTTTCATCGTTGGTGGAGCCTTTGATGGAATTGAAGAAATTGTGAAGCAACGTCTTGGTGAAAAGATTAT
CGGATTTGGGAAAAATAACAAAGCCATTGATGAATCCAGCTCTTATATGCAAGAAATCATTGCAGAAGATATTCAAAAAT
TCGGTATTATTCCTGAGTTAATCGGTCGTCTTCCTGTTCTTGCTGCATTAGAGCAATTGACAGTGGATGACTTGGTTCGT
ATTTTGAAAGAACCAAGAAATGCCTTGGTGAAACAATACCAAGCTCTCTTATCCTTTGATGATGTTGAATTAGAATTTGA
TGACGAAGCACTTGAAGAGATTGCAAGTAAAGCTATCGAACGCAAGACAGGTGCTCGTGGACTACGCTCTATCATCGAAG
AAACTATGTTGGATGTGATGTTTGAAGTTCCAAGTCAAGAAGACGTCAAACTGGTTCGAATCACTAAAGAAGCAGTTAAC
GGAACCGAAAAACCAATTTTAGAAACTGCCTAG

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (111-306)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (313-390)

3D structure

• AlphaFold DB: E7SB47

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	87.317	100	0.873
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.209	98.049	0.571