Detailed information NTG1141333

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQN32_RS04065
• Genome accession: NZ_LS483432
• Coordinates: 755322..756551 (+)
• Length: 409 a.a.
• NCBI ID: WP_031488352.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13745
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 750322..761551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN32_RS04040 (NCTC13745_00797)	-	750938..752215 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
DQN32_RS04045 (NCTC13745_00798)	-	752202..753377 (-)	1176	WP_031488354.1	hydroxymethylglutaryl-CoA synthase	-
DQN32_RS04050 (NCTC13745_00799)	-	753586..754425 (+)	840	WP_011017679.1	thymidylate synthase	-
DQN32_RS04055 (NCTC13745_00800)	-	754505..755002 (+)	498	WP_031488353.1	dihydrofolate reductase	-
DQN32_RS04065 (NCTC13745_00802)	clpX	755322..756551 (+)	1230	WP_031488352.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQN32_RS04070 (NCTC13745_00803)	yihA	756561..757160 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQN32_RS04075 (NCTC13745_00804)	-	757308..758051 (+)	744	WP_002984942.1	hypothetical protein	-
DQN32_RS04080 (NCTC13745_00805)	-	758109..760208 (-)	2100	WP_031488351.1	AAA family ATPase	-
DQN32_RS04085 (NCTC13745_00806)	rpiA	760586..761269 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44991.48 Da
• Isoelectric Point: 4.6184

>NTDB_id=1141333 DQN32_RS04065 WP_031488352.1 755322..756551(+) (clpX) [Streptococcus pyogenes strain NCTC13745]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1141333 DQN32_RS04065 WP_031488352.1 755322..756551(+) (clpX) [Streptococcus pyogenes strain NCTC13745]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGTCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTTTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTAAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575