Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPOKI102_RS02800 Genome accession   NZ_CP006820
Coordinates   576282..578066 (-) Length   594 a.a.
NCBI ID   WP_025275827.1    Uniprot ID   -
Organism   Helicobacter pylori oki102     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 571282..583066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPOKI102_RS02770 (HPOKI102_02900) - 571686..571934 (+) 249 WP_000790557.1 RNA-binding protein -
  HPOKI102_RS02775 (HPOKI102_02905) - 572133..572954 (-) 822 WP_025275825.1 glycosyltransferase family 25 protein -
  HPOKI102_RS02780 (HPOKI102_02915) trxB 573311..574246 (-) 936 WP_000564419.1 thioredoxin-disulfide reductase -
  HPOKI102_RS02785 (HPOKI102_02920) trxA 574252..574572 (-) 321 WP_000020199.1 thioredoxin -
  HPOKI102_RS02790 (HPOKI102_02925) - 574661..575005 (-) 345 WP_015427936.1 YraN family protein -
  HPOKI102_RS02795 (HPOKI102_02930) - 575006..576271 (-) 1266 WP_025275826.1 homoserine dehydrogenase -
  HPOKI102_RS02800 (HPOKI102_02935) uvrC 576282..578066 (-) 1785 WP_025275827.1 excinuclease ABC subunit UvrC Machinery gene
  HPOKI102_RS02805 (HPOKI102_02940) - 578067..578528 (-) 462 WP_025275828.1 hypothetical protein -
  HPOKI102_RS02810 (HPOKI102_02945) - 578520..578699 (+) 180 WP_000468792.1 hypothetical protein -
  HPOKI102_RS02815 (HPOKI102_02950) - 578711..579352 (-) 642 WP_025275829.1 ATP-binding cassette domain-containing protein -
  HPOKI102_RS02820 (HPOKI102_02955) - 579356..581017 (-) 1662 WP_025275830.1 ABC transporter permease/substrate-binding protein -
  HPOKI102_RS02825 (HPOKI102_02960) - 581086..581532 (-) 447 WP_001081241.1 hypothetical protein -
  HPOKI102_RS02830 (HPOKI102_02965) motB 581529..582302 (-) 774 WP_025275831.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68603.83 Da        Isoelectric Point: 9.6316

>NTDB_id=114131 HPOKI102_RS02800 WP_025275827.1 576282..578066(-) (uvrC) [Helicobacter pylori oki102]
MADLLSSLKNLPHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSICNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=114131 HPOKI102_RS02800 WP_025275827.1 576282..578066(-) (uvrC) [Helicobacter pylori oki102]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
GCTCTATATCGGTAAAGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCTGCAATAATGAAATCACGCCCA
ACCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACGATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAATATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAGTTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCCAATAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGACATTTTTGCTTTTTATGGCGCGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATTCTATTAAAC
GCTTGTTCTAATGAAGCGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGAGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

98.485

100

0.985

Multiple sequence alignment