Detailed information NTG1141255

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: DQN28_RS01395
• Genome accession: NZ_LS483430
• Coordinates: 254182..255252 (+)
• Length: 356 a.a.
• NCBI ID: WP_002986002.1
• Uniprot ID: Q1JNF7
• Organism: Streptococcus pyogenes strain NCTC12044
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 249182..260252

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN28_RS01380 (NCTC12044_00273)	amiA	249710..251680 (+)	1971	WP_024623426.1	peptide ABC transporter substrate-binding protein	Regulator
DQN28_RS01385 (NCTC12044_00274)	amiC	251745..253247 (+)	1503	WP_011017334.1	ABC transporter permease	Regulator
DQN28_RS01390 (NCTC12044_00275)	amiD	253247..254173 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
DQN28_RS01395 (NCTC12044_00276)	amiE	254182..255252 (+)	1071	WP_002986002.1	ABC transporter ATP-binding protein	Regulator
DQN28_RS01400 (NCTC12044_00277)	amiF	255245..256168 (+)	924	WP_111686167.1	ABC transporter ATP-binding protein	Regulator
DQN28_RS09300	-	256206..256289 (-)	84	Protein_224	IS3 family transposase	-
DQN28_RS08990	-	256316..256561 (-)	246	WP_197712548.1	transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39749.85 Da
• Isoelectric Point: 5.7015

>NTDB_id=1141255 DQN28_RS01395 WP_002986002.1 254182..255252(+) (amiE) [Streptococcus pyogenes strain NCTC12044]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGRQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=1141255 DQN28_RS01395 WP_002986002.1 254182..255252(+) (amiE) [Streptococcus pyogenes strain NCTC12044]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGACAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: Q1JNF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.389	100	0.772
amiE	Streptococcus thermophilus LMG 18311	75.278	100	0.761
amiE	Streptococcus thermophilus LMD-9	75.278	100	0.761
oppD	Streptococcus mutans UA159	56.677	94.663	0.537