Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQN36_RS05630 Genome accession   NZ_LS483425
Coordinates   1110964..1112193 (-) Length   409 a.a.
NCBI ID   WP_023609877.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC13737     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1105964..1117193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN36_RS05610 (NCTC13737_01110) rpiA 1106246..1106929 (-) 684 WP_002994002.1 ribose-5-phosphate isomerase RpiA -
  DQN36_RS05615 (NCTC13737_01111) - 1107307..1109406 (+) 2100 WP_111704238.1 AAA family ATPase -
  DQN36_RS05620 (NCTC13737_01112) - 1109464..1110207 (-) 744 WP_002984942.1 hypothetical protein -
  DQN36_RS05625 (NCTC13737_01113) yihA 1110355..1110954 (-) 600 WP_011184414.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQN36_RS05630 (NCTC13737_01114) clpX 1110964..1112193 (-) 1230 WP_023609877.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQN36_RS05635 (NCTC13737_01115) - 1112323..1112493 (-) 171 WP_002990165.1 hypothetical protein -
  DQN36_RS05640 (NCTC13737_01116) - 1112513..1113010 (-) 498 WP_002984955.1 dihydrofolate reductase -
  DQN36_RS05645 (NCTC13737_01117) - 1113090..1113929 (-) 840 WP_011017679.1 thymidylate synthase -
  DQN36_RS05650 (NCTC13737_01118) - 1114138..1115313 (+) 1176 WP_023609855.1 hydroxymethylglutaryl-CoA synthase -
  DQN36_RS05655 (NCTC13737_01119) - 1115300..1116577 (+) 1278 WP_020833420.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45045.62 Da        Isoelectric Point: 4.6616

>NTDB_id=1141149 DQN36_RS05630 WP_023609877.1 1110964..1112193(-) (clpX) [Streptococcus pyogenes strain NCTC13737]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKISDLIRI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1141149 DQN36_RS05630 WP_023609877.1 1110964..1112193(-) (clpX) [Streptococcus pyogenes strain NCTC13737]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAATATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.998

100

0.89
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.603

98.044

0.575

Multiple sequence alignment