Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQN40_RS04480 Genome accession   NZ_LS483413
Coordinates   852751..854076 (+) Length   441 a.a.
NCBI ID   WP_015017291.1    Uniprot ID   A0A9X8T4I6
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 847751..859076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN40_RS04455 (NCTC7136_00917) - 848428..849069 (+) 642 WP_014612503.1 response regulator transcription factor -
  DQN40_RS04460 (NCTC7136_00918) - 849106..850506 (+) 1401 WP_042357970.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQN40_RS04465 (NCTC7136_00919) - 850506..850865 (+) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  DQN40_RS04470 (NCTC7136_00920) cysK 851018..851953 (-) 936 WP_084916480.1 cysteine synthase A -
  DQN40_RS04475 (NCTC7136_00921) - 852057..852695 (-) 639 WP_084916482.1 YigZ family protein -
  DQN40_RS04480 (NCTC7136_00922) comFA/cflA 852751..854076 (+) 1326 WP_015017291.1 DEAD/DEAH box helicase Machinery gene
  DQN40_RS11670 (NCTC7136_00923) - 854048..854713 (+) 666 WP_012767419.1 ComF family protein -
  DQN40_RS04490 (NCTC7136_00924) raiA 854793..855341 (+) 549 WP_084916484.1 ribosome-associated translation inhibitor RaiA -
  DQN40_RS04495 (NCTC7136_00925) - 855471..856439 (+) 969 WP_111679497.1 IS30 family transposase -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49283.45 Da        Isoelectric Point: 9.7069

>NTDB_id=1140706 DQN40_RS04480 WP_015017291.1 852751..854076(+) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVAIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYLNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1140706 DQN40_RS04480 WP_015017291.1 852751..854076(+) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
ATGGAAGGTATCGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAGCCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGTGGCACTTACTACTGCCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACGCCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGAGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGTTGACATTAGCTAGACGATTCCACGATAATCCTTTAAT
TCTTCCGAAATTTATCAGGAGTTTTGGTCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAACAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGTATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTTGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-396)

DEAD/DEAH box helicase (DEAD)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae D39

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae R6

53.302

96.145

0.512
  comFA/cflA Streptococcus pneumoniae TIGR4

53.302

96.145

0.512
  comFA/cflA Streptococcus mitis NCTC 12261

51.852

97.959

0.508
  comFA/cflA Streptococcus mitis SK321

52.214

97.279

0.508
  comFA Lactococcus lactis subsp. cremoris KW2

46.465

89.796

0.417
  comFA Latilactobacillus sakei subsp. sakei 23K

37.587

97.732

0.367

Multiple sequence alignment