Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DQN21_RS11945 Genome accession   NZ_LS483409
Coordinates   2377949..2380390 (-) Length   813 a.a.
NCBI ID   WP_077497892.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2372949..2385390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS11925 (NCTC13773_02421) - 2373435..2374649 (-) 1215 WP_077497890.1 YcaO-like family protein -
  DQN21_RS11930 (NCTC13773_02422) - 2374646..2375515 (-) 870 WP_009855133.1 hypothetical protein -
  DQN21_RS12645 - 2375612..2375752 (-) 141 WP_012962614.1 hypothetical protein -
  DQN21_RS11935 (NCTC13773_02423) hslO 2376039..2376905 (+) 867 WP_009855134.1 Hsp33 family molecular chaperone HslO -
  DQN21_RS11940 (NCTC13773_02424) dusB 2376898..2377875 (+) 978 WP_009855135.1 tRNA dihydrouridine synthase DusB -
  DQN21_RS11945 (NCTC13773_02425) clpC 2377949..2380390 (-) 2442 WP_077497892.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQN21_RS11950 (NCTC13773_02426) - 2380387..2380848 (-) 462 WP_003066826.1 CtsR family transcriptional regulator -
  DQN21_RS12895 - 2381131..2381253 (+) 123 WP_257787376.1 hypothetical protein -
  DQN21_RS11960 (NCTC13773_02427) - 2381561..2382025 (+) 465 WP_009855139.1 COG2426 family protein -
  DQN21_RS11965 (NCTC13773_02428) - 2382140..2383000 (-) 861 WP_009855140.1 helix-turn-helix domain-containing protein -
  DQN21_RS11970 (NCTC13773_02429) - 2383042..2384238 (-) 1197 WP_061458152.1 MFS transporter -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90110.51 Da        Isoelectric Point: 5.8514

>NTDB_id=1140592 DQN21_RS11945 WP_077497892.1 2377949..2380390(-) (clpC) [Streptococcus gallolyticus strain NCTC13773]
MSEYSIKMQEVFSVAQYQAARFESPYLESWHVLLAMVAIHDSVAGLTFAEYQTKIVYEEYEAAAVLAIGKSPLTDVDRVH
FVEQSKALSDVLAFAESICQVTGGNEIGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDAVRLIDLRKSLARNAGFTKE
NIKAIHELRKPKKSTMGGAFSEMMKPQSTAGDLSDFTRDLTEMARQGKLEPVIGREKEISRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGAIPYELQGMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEEDGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHLEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYEDFHNVVISDE
AVLTAVKAAHRYLTSKNLPDSAIDLLDEASATVQGLVKKEAPATLTPADKAILEGDFKLATKLLKESRKKPNRKPTAVTE
DDIMATLSRLSGIPVEKMTQADSKKYLNLEKELHKRVIGQDSAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDEKTVGFGARDMAHDYEAMQKRIMEELKKAYRPEFINRIDEKVVFHN
LTQENMRDVVKIMVKPLIATLAEKDITLKFQPSALKYLAEIGYDPEMGARPLRRTLQDKVEDELSELILSGELASGNTLK
IGVSKGQLKFDIA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=1140592 DQN21_RS11945 WP_077497892.1 2377949..2380390(-) (clpC) [Streptococcus gallolyticus strain NCTC13773]
ATGAGTGAGTATTCGATAAAAATGCAAGAGGTTTTCAGTGTTGCTCAATACCAAGCAGCGCGTTTTGAAAGCCCATATTT
AGAAAGTTGGCACGTCCTTTTAGCCATGGTTGCTATCCATGACTCAGTCGCAGGGCTAACATTTGCGGAATACCAAACTA
AAATCGTCTATGAAGAGTATGAAGCGGCAGCTGTTTTAGCCATTGGGAAATCACCGTTAACGGATGTTGACAGAGTTCAT
TTTGTAGAGCAATCTAAAGCTCTTAGTGATGTTTTAGCATTTGCTGAGTCTATTTGTCAGGTGACTGGTGGTAACGAAAT
CGGGACAGAACACGTGCTTTATGCGATGTTGTTAAACCTTGATTTATTTGCCACACGTTTGTTAGAAGTTGCTGGTTTTA
AAAACAAAGAAGACGGTGACGCTGTTCGTTTGATTGATTTGCGTAAGAGTTTGGCACGTAATGCTGGTTTTACAAAGGAA
AATATCAAAGCTATTCATGAACTTCGTAAGCCGAAAAAATCGACAATGGGCGGTGCTTTTTCTGAAATGATGAAACCACA
GTCAACAGCGGGGGATTTGTCAGATTTCACGCGTGATTTGACAGAGATGGCACGTCAAGGAAAATTAGAGCCTGTTATCG
GTCGTGAAAAAGAAATTTCTCGTATGGTGCAGGTGCTCAGCCGCAAAACGAAAAACAATCCAGTTTTAGTAGGGGAAGCT
GGTGTTGGTAAAACGGCTCTTGCTTACGGTTTGGCACAGCGAATTGTCAATGGTGCGATTCCGTATGAACTCCAAGGCAT
GCGTGTTTTAGAGCTTGATATGATGAGCGTTGTGGCTGGTACGCGATTCCGTGGTGATTTTGAAGAACGCATGAACCAAA
TCATCTCAGATATTGAGGAAGACGGTCATATTATTCTTTTCATTGACGAAGTGCATACGATTATGGGTTCAGGCTCTGGA
ATTGACAGCACTTTGGATGCGGCTAATATTCTAAAACCAGCGCTTGCGCGTGGTACGCTTCATATGGTTGGTGCGACAAC
GCAAGAAGAATATCAAAAACATCTTGAAAAAGATGCGGCGCTTTCTCGCCGTTTTGCTAAGATTACCATTGAAGAACCAA
GTGTTGAAGATGCTTACCAAATCTTGCTTGGGTTAAAGAAATCATATGAAGATTTTCATAATGTGGTGATTTCTGACGAA
GCTGTTTTAACGGCTGTCAAAGCTGCGCATCGCTATTTGACAAGTAAAAATCTTCCTGACTCAGCGATTGATTTGCTTGA
TGAAGCAAGTGCAACGGTTCAAGGTCTGGTGAAAAAAGAAGCGCCAGCTACTTTGACACCTGCTGATAAAGCTATTTTGG
AAGGTGATTTCAAATTGGCAACGAAATTGCTGAAAGAGTCACGCAAGAAGCCAAATCGTAAACCAACTGCTGTGACAGAA
GATGATATTATGGCAACGCTCAGTCGTTTGTCAGGTATTCCTGTTGAGAAAATGACACAGGCAGATAGTAAGAAATACTT
GAACCTCGAAAAAGAACTCCATAAGCGTGTGATTGGCCAAGATTCAGCTATTTCAGCGATTAGTCGTGCTATTCGTCGTA
ATCAAGCGGGCATTCGTACAGGCAAACGTCCGATTGGGTCGTTTATGTTCTTGGGCCCAACGGGTGTTGGTAAAACAGAG
TTGGCTAAGGCACTAGCAGAATTGCTATTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATATGGAAAA
ATTTGCGGCGAGCCGTCTTAACGGAGCTCCTCCAGGATATGTCGGTTACGAAGAAGGTGGCGAATTGACTGAAAAAGTTC
GCAACAAACCTTATTCTGTGCTTCTATTTGATGAAGTTGAAAAAGCCCACCCAGATATTTTCAATGTGCTTCTCCAAGTG
TTGGATGACGGTGTGCTGACGGATAGTCGTGGTCGTAAAGTTGATTTTTCAAACACGATTATCATCATGACGTCAAATCT
TGGAGCAACCGCTTTGCGTGATGAAAAGACAGTTGGTTTTGGTGCGCGTGATATGGCTCATGATTATGAGGCAATGCAAA
AACGCATCATGGAAGAACTCAAAAAAGCTTACCGACCTGAATTCATCAACCGTATTGATGAAAAGGTTGTTTTCCACAAC
TTAACTCAAGAAAATATGCGTGATGTCGTGAAAATCATGGTTAAACCATTGATTGCGACACTAGCTGAAAAAGATATTAC
GCTAAAATTCCAACCATCAGCATTGAAATATTTAGCCGAAATTGGATACGACCCAGAAATGGGAGCTCGTCCGCTCCGCC
GTACTCTGCAAGATAAAGTTGAAGATGAATTATCAGAGCTTATTCTATCAGGCGAATTGGCAAGTGGAAATACCCTTAAA
ATCGGCGTTTCTAAAGGGCAACTCAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(235-366)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(95-134)

AAA lid domain (AAA_lid_9)

(374-452)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

77.094

99.877

0.77
  clpC Streptococcus thermophilus LMG 18311

73.497

100

0.737
  clpC Streptococcus thermophilus LMD-9

73.374

100

0.736
  clpC Streptococcus pneumoniae TIGR4

68.054

100

0.684
  clpC Streptococcus pneumoniae Rx1

68.054

100

0.684
  clpC Streptococcus pneumoniae D39

68.054

100

0.684
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

49.34

100

0.506
  clpC Bacillus subtilis subsp. subtilis str. 168

43.735

100

0.446
  clpE Streptococcus pneumoniae TIGR4

45.95

78.967

0.363
  clpE Streptococcus pneumoniae Rx1

45.95

78.967

0.363
  clpE Streptococcus pneumoniae D39

45.95

78.967

0.363
  clpE Streptococcus pneumoniae R6

45.95

78.967

0.363
  clpE Streptococcus mutans UA159

47.334

76.138

0.36

Multiple sequence alignment