Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQN21_RS06915 Genome accession   NZ_LS483409
Coordinates   1364343..1365572 (-) Length   409 a.a.
NCBI ID   WP_009854360.1    Uniprot ID   A0AA94SA95
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1359343..1370572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS06890 (NCTC13773_01400) - 1359638..1360285 (+) 648 WP_009854355.1 endonuclease III domain-containing protein -
  DQN21_RS06895 (NCTC13773_01401) - 1360394..1361062 (+) 669 WP_009854356.1 YoaK family protein -
  DQN21_RS06900 (NCTC13773_01402) mmuM 1361102..1362052 (-) 951 WP_009854357.1 homocysteine S-methyltransferase -
  DQN21_RS06905 (NCTC13773_01403) - 1362065..1363441 (-) 1377 WP_077496984.1 amino acid permease -
  DQN21_RS06910 (NCTC13773_01404) yihA 1363739..1364332 (-) 594 WP_012962046.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQN21_RS06915 (NCTC13773_01405) clpX 1364343..1365572 (-) 1230 WP_009854360.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQN21_RS06920 (NCTC13773_01406) - 1365605..1365775 (-) 171 WP_003065196.1 hypothetical protein -
  DQN21_RS06925 (NCTC13773_01407) - 1365792..1366286 (-) 495 WP_009854361.1 dihydrofolate reductase -
  DQN21_RS06930 (NCTC13773_01408) - 1366374..1367213 (-) 840 WP_009854362.1 thymidylate synthase -
  DQN21_RS06935 (NCTC13773_01409) - 1367534..1368712 (+) 1179 WP_009854363.1 hydroxymethylglutaryl-CoA synthase -
  DQN21_RS06940 (NCTC13773_01410) - 1368687..1369970 (+) 1284 WP_009854364.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45212.91 Da        Isoelectric Point: 4.5644

>NTDB_id=1140567 DQN21_RS06915 WP_009854360.1 1364343..1365572(-) (clpX) [Streptococcus gallolyticus strain NCTC13773]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQDR
AKRALAVAVYNHYKRVSFAESRNEEDVDLQKSNILMIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFCQNNRKIDENASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDKDALQAIANKAIERKIGARGLRSIIEETMMDIMFEIPSQEEVTKVRITKAAVEG
KDKPILEIA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1140567 DQN21_RS06915 WP_009854360.1 1364343..1365572(-) (clpX) [Streptococcus gallolyticus strain NCTC13773]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTCTGTGGAAAAAGCCAAGATGAAGTAAAAAAAATCAT
TGCAGGAAACAATGTTTTTATCTGTAATGAGTGTGTGGCTTTGTCACAAGAAATTATCAAAGAAGAACTTGCTGAGGAAG
TTCTTGCAGATTTAGCGGAAGTTCCAAAACCTAAAGAGTTGTTAGCAACTCTTGACGAATATGTCGTTGGTCAAGACCGT
GCCAAACGCGCGCTTGCCGTAGCTGTTTATAACCATTACAAACGTGTTTCTTTTGCGGAAAGTCGCAACGAAGAAGATGT
TGATTTGCAAAAATCAAACATTTTGATGATTGGTCCTACAGGCTCAGGAAAAACATTCCTAGCTCAAACTTTGGCTAAAA
CATTGAATGTACCGTTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGATGTTGAAAATATC
CTCTTGAAATTAATTCAAGCAGCTGATTTTAATATCGAACGCGCCGAACGCGGTATTATTTACGTGGATGAAATTGATAA
AATCGCTAAAAAAGGTGAAAATGTCTCAATTACACGTGATGTTTCAGGTGAAGGTGTTCAACAAGCACTTCTTAAAATCA
TTGAAGGAACAGTTGCTAGCGTACCACCTCAAGGTGGACGTAAGCACCCTAACCAAGAAATGATTCAAATTGACACTAAA
AATATCCTATTCATTGTCGGCGGTGCTTTTGATGGTATCGAAGATATTGTCAAACAACGTTTAGGTGAAAAGGTTATCGG
TTTTTGTCAAAATAACCGTAAAATTGATGAAAATGCTTCTTATATGCAAGAAATCATTTCAGAGGATATTCAAAAATTTG
GCTTGATTCCAGAATTTATCGGACGTTTGCCAGTTGTAGCGGCACTTGAACAGTTGACGGCTGATGATTTGGTTCGTATC
TTGACAGAACCACGTAATGCCTTGGTTAAACAATATCAAACGCTATTATCATACGACGGTGTTGAACTAGAATTTGATAA
AGATGCTTTGCAAGCTATTGCTAACAAAGCCATTGAACGCAAGATAGGAGCTCGTGGTTTACGCTCAATTATTGAAGAAA
CTATGATGGATATCATGTTTGAAATTCCTAGCCAAGAAGAAGTGACTAAGGTTCGTATCACTAAAGCGGCTGTTGAAGGC
AAAGACAAACCAATTTTGGAAATTGCGTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.487

100

0.895
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.354

98.044

0.572

Multiple sequence alignment