Detailed information NTG1140352

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQN23_RS05040
• Genome accession: NZ_LS483403
• Coordinates: 987413..988642 (-)
• Length: 409 a.a.
• NCBI ID: WP_020916897.1
• Uniprot ID: A0AB33AMD1
• Organism: Streptococcus lutetiensis strain NCTC13774
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 982413..993642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN23_RS05020 (NCTC13774_01047)	-	983634..984302 (+)	669	WP_043895254.1	YoaK family protein	-
DQN23_RS05025	mmuM	984335..985281 (-)	947	Protein_926	homocysteine S-methyltransferase	-
DQN23_RS05030	-	985292..986700 (-)	1409	Protein_927	amino acid permease	-
DQN23_RS05035 (NCTC13774_01054)	yihA	986809..987402 (-)	594	WP_043895055.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQN23_RS05040 (NCTC13774_01055)	clpX	987413..988642 (-)	1230	WP_020916897.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQN23_RS05050 (NCTC13774_01057)	-	988869..989363 (-)	495	WP_020916898.1	dihydrofolate reductase	-
DQN23_RS05055 (NCTC13774_01058)	-	989446..990285 (-)	840	WP_111712847.1	thymidylate synthase	-
DQN23_RS05060 (NCTC13774_01059)	-	990613..991788 (+)	1176	WP_058813991.1	hydroxymethylglutaryl-CoA synthase	-
DQN23_RS05065 (NCTC13774_01060)	-	991778..993049 (+)	1272	WP_111712848.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45224.79 Da
• Isoelectric Point: 4.5119

>NTDB_id=1140352 DQN23_RS05040 WP_020916897.1 987413..988642(-) (clpX) [Streptococcus lutetiensis strain NCTC13774]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSRVEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=1140352 DQN23_RS05040 WP_020916897.1 987413..988642(-) (clpX) [Streptococcus lutetiensis strain NCTC13774]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAAATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATACAACCACTACAAACGTGTTTCATTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTGCAAAAATCTAACATCTTATTGATTGGACCAACTGGTTCAGGGAAAACTTTCCTTGCTCAAACCTTGGCGAAAA
GTTTAAACGTTCCATTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGACGTTGAAAATATC
CTTTTGAAACTCATTCAAGCAGCTGATTTTAATATTGAACGCGCAGAACGTGGTATCATCTACGTGGATGAAATTGATAA
AATTGCCAAAAAAGGTGAAAATGTCTCAATCACTCGTGATGTTTCAGGCGAAGGTGTTCAACAAGCTCTTCTTAAAATTA
TTGAAGGAACAGTTGCTAGCGTGCCACCACAAGGTGGTCGTAAACACCCGAACCAAGAAATGATTCAAATCAATACTAAG
AATATCCTTTTCATCGTTGGTGGTGCTTTTGACGGTATTGAAGATATTGTTAAACAACGTCTCGGTGAAAAAGTTATTGG
TTTTGGTCAAAATAACCGTAAGATCGATGAAGATGCTTCTTATATGCAAGAAATTATCTCGGAAGATATTCAGAAATTTG
GTTTAATTCCTGAATTTATCGGACGTTTGCCAGTCGTTGCTGCCCTTGAACAATTGACAACAGATGATTTGGTACGAATC
TTGACAGAACCTCGTAATGCCTTGGTTAAACAATACCAAACGCTTCTATCATATGATGGTGTTGAGTTGGAATTTGATGA
AGATGCCCTTCAAGCTATTGCTAATAAAGCAATCGAACGTAAGACAGGTGCACGTGGACTTCGTTCAATCATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGTAGAGGTCACTAAAGTCCGTATTACAAAAGATGCCGTTGAAGGC
AAAGATAAACCAATTTTAGAGATTGCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577