Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   DQM80_RS09640 Genome accession   NZ_LS483399
Coordinates   48029..48124 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8227     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 43029..53124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM80_RS00250 (NCTC8227_00051) - 43901..45241 (+) 1341 WP_111701713.1 hypothetical protein -
  DQM80_RS00255 (NCTC8227_00052) purB 45610..46902 (+) 1293 WP_002987723.1 adenylosuccinate lyase -
  DQM80_RS00260 (NCTC8227_00053) comR 47034..47945 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  DQM80_RS09640 (NCTC8227_00054) comS 48029..48124 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  DQM80_RS00265 (NCTC8227_00055) ruvB 48171..49169 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  DQM80_RS00270 (NCTC8227_00056) - 49307..49744 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  DQM80_RS00275 (NCTC8227_00057) - 49767..50168 (+) 402 WP_011017240.1 MORN repeat-containing protein -
  DQM80_RS00280 (NCTC8227_00058) - 50165..51940 (+) 1776 WP_002986669.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=1140257 DQM80_RS09640 WP_198462994.1 48029..48124(+) (comS) [Streptococcus pyogenes strain NCTC8227]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=1140257 DQM80_RS09640 WP_198462994.1 48029..48124(+) (comS) [Streptococcus pyogenes strain NCTC8227]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452


Multiple sequence alignment