Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM95_RS07615 Genome accession   NZ_LS483397
Coordinates   1481994..1483295 (-) Length   433 a.a.
NCBI ID   WP_037593421.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC3858     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1476994..1488295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM95_RS07605 (NCTC3858_01549) hpf 1480706..1481254 (-) 549 WP_037593419.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQM95_RS07610 (NCTC3858_01550) - 1481330..1482004 (-) 675 WP_037593420.1 ComF family protein -
  DQM95_RS07615 (NCTC3858_01551) comFA/cflA 1481994..1483295 (-) 1302 WP_037593421.1 DEAD/DEAH box helicase Machinery gene
  DQM95_RS07620 (NCTC3858_01552) - 1483352..1483981 (+) 630 WP_015911698.1 YigZ family protein -
  DQM95_RS07625 (NCTC3858_01553) cysK 1484090..1485022 (+) 933 WP_037593422.1 cysteine synthase A -
  DQM95_RS07630 (NCTC3858_01554) - 1485037..1485393 (-) 357 WP_015911700.1 S1 RNA-binding domain-containing protein -
  DQM95_RS07635 (NCTC3858_01555) - 1485393..1486793 (-) 1401 WP_037593423.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM95_RS07640 (NCTC3858_01556) - 1486827..1487468 (-) 642 WP_015911702.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 50094.43 Da        Isoelectric Point: 10.1114

>NTDB_id=1140174 DQM95_RS07615 WP_037593421.1 1481994..1483295(-) (comFA/cflA) [Streptococcus uberis strain NCTC3858]
MDELNVYDGRRFTPYQVPKQLLQYASVQDSMYKEGSKWFCGRCHMPVSNKNKLPNGHYYCRECIIFGRNESHSHLYTFPA
RPFPNTQALKWMGQLTPFQEKISRQLVSESKKKQKRLVHAVTGAGKTEMIYGLITSYLNEGKWVCIASPRIDVCIELYGR
LKNDFTCPITLMHGESEVYHKSPLIVATTHQLLKFYRAFDLMVIDEVDSFPFVGNSILSRAVTSALKEEGEILYLTATST
KELDLKVKRGDIEKLTLPRRFHNQPLIVPKFKLILNLEESLQKKRLPIPLLNMIRRQRKTNYPLLIFHPIIDKGEEFFRL
LATKLRNEKIAYVSSQSDHRKQIIEQFRKSEISILITTTILERGVTFPGVDVFVLLSHHKLFNASSLIQISGRVGRSLDR
PTGQLFFLHQGISIDMLKAKKEIIRMNREAYGQ

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1140174 DQM95_RS07615 WP_037593421.1 1481994..1483295(-) (comFA/cflA) [Streptococcus uberis strain NCTC3858]
ATGGATGAATTAAATGTTTACGATGGTCGTCGCTTCACTCCTTACCAAGTTCCAAAACAGTTATTGCAGTATGCAAGTGT
TCAAGATAGTATGTACAAAGAGGGTTCTAAGTGGTTTTGTGGCAGATGTCATATGCCTGTTTCAAATAAAAACAAGTTAC
CTAATGGTCACTACTATTGTAGGGAATGTATTATTTTCGGTCGAAATGAGAGTCATTCTCACCTTTATACTTTTCCGGCT
AGGCCATTTCCTAACACTCAGGCTCTAAAGTGGATGGGACAATTAACACCATTTCAAGAAAAAATATCGCGTCAGCTTGT
CTCAGAATCAAAGAAAAAACAAAAGCGACTGGTGCATGCTGTTACTGGTGCAGGCAAAACGGAGATGATTTATGGATTAA
TAACTTCTTATCTTAATGAAGGAAAATGGGTTTGTATAGCTAGTCCGCGTATTGATGTTTGTATTGAACTGTACGGTCGC
TTAAAAAATGATTTTACCTGTCCAATTACGCTGATGCATGGAGAATCAGAAGTCTATCACAAAAGTCCCTTAATCGTTGC
TACGACGCATCAGTTGTTAAAGTTTTATCGGGCCTTTGATTTAATGGTTATTGATGAAGTTGATTCATTCCCGTTCGTGG
GGAATAGCATCTTGAGTCGGGCTGTTACTTCAGCTTTAAAAGAGGAGGGTGAAATCCTTTATCTTACGGCTACCTCGACT
AAAGAGCTTGATTTGAAAGTGAAAAGAGGTGATATTGAGAAACTAACATTACCTAGACGATTCCATAATCAACCCTTGAT
TGTCCCTAAATTTAAACTTATCCTTAATTTGGAAGAATCATTACAAAAAAAGCGTCTCCCTATTCCGTTATTGAACATGA
TTCGAAGGCAAAGAAAAACAAATTACCCACTATTAATTTTTCATCCCATTATAGATAAGGGTGAGGAGTTTTTTCGTTTA
TTAGCAACTAAACTGAGGAATGAAAAGATTGCCTATGTTTCAAGTCAATCCGATCATAGAAAGCAGATAATTGAACAATT
TAGGAAATCAGAAATATCTATTTTAATCACGACAACAATCCTAGAAAGAGGCGTAACCTTTCCAGGTGTAGATGTGTTTG
TGCTTTTGTCTCATCACAAATTATTTAATGCGTCTAGCCTTATACAAATTTCGGGACGCGTTGGAAGATCTCTTGATCGC
CCAACGGGGCAGCTATTTTTCTTACATCAAGGAATTAGCATAGATATGTTAAAAGCCAAAAAAGAAATTATCAGGATGAA
TAGGGAGGCATATGGACAATAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(95-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae D39

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae R6

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae TIGR4

54.009

97.921

0.529
  comFA/cflA Streptococcus mitis NCTC 12261

53.538

97.921

0.524
  comFA/cflA Streptococcus mitis SK321

53.302

97.921

0.522
  comFA Lactococcus lactis subsp. cremoris KW2

49.62

91.224

0.453
  comFA Latilactobacillus sakei subsp. sakei 23K

37.162

100

0.381

Multiple sequence alignment