Detailed information NTG1139986

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQN61_RS03945
• Genome accession: NZ_LS483391
• Coordinates: 733756..734985 (+)
• Length: 409 a.a.
• NCBI ID: WP_072135786.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8320
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 728756..739985

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN61_RS03920 (NCTC8320_00779)	-	729372..730649 (-)	1278	WP_011017677.1	hydroxymethylglutaryl-CoA reductase, degradative	-
DQN61_RS03925 (NCTC8320_00780)	-	730636..731811 (-)	1176	WP_011017678.1	hydroxymethylglutaryl-CoA synthase	-
DQN61_RS03930 (NCTC8320_00781)	-	732020..732859 (+)	840	WP_011017679.1	thymidylate synthase	-
DQN61_RS03935 (NCTC8320_00782)	-	732939..733436 (+)	498	WP_011017680.1	dihydrofolate reductase	-
DQN61_RS03940 (NCTC8320_00783)	-	733456..733626 (+)	171	WP_002990165.1	hypothetical protein	-
DQN61_RS03945 (NCTC8320_00784)	clpX	733756..734985 (+)	1230	WP_072135786.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQN61_RS03950 (NCTC8320_00785)	yihA	734995..735594 (+)	600	WP_011017681.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQN61_RS03955 (NCTC8320_00786)	-	735742..736485 (+)	744	WP_002984942.1	hypothetical protein	-
DQN61_RS03960 (NCTC8320_00787)	-	736543..738642 (-)	2100	WP_011017682.1	AAA family ATPase	-
DQN61_RS03965 (NCTC8320_00788)	rpiA	739020..739703 (+)	684	WP_011017683.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45063.50 Da
• Isoelectric Point: 4.5487

>NTDB_id=1139986 DQN61_RS03945 WP_072135786.1 733756..734985(+) (clpX) [Streptococcus pyogenes strain NCTC8320]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAENNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1139986 DQN61_RS03945 WP_072135786.1 733756..734985(+) (clpX) [Streptococcus pyogenes strain NCTC8320]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATATTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGAAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCTAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGAGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTGTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTGCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575