Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM45_RS07920 Genome accession   NZ_LS483388
Coordinates   1586628..1587929 (-) Length   433 a.a.
NCBI ID   WP_003084125.1    Uniprot ID   A0A4V0HAX3
Organism   Streptococcus porcinus strain NCTC10999     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1581628..1592929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM45_RS07910 (NCTC10999_01610) hpf 1585335..1585883 (-) 549 WP_003082693.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQM45_RS07915 (NCTC10999_01611) - 1585958..1586638 (-) 681 WP_003085727.1 ComF family protein -
  DQM45_RS07920 (NCTC10999_01612) comFA/cflA 1586628..1587929 (-) 1302 WP_003084125.1 DEAD/DEAH box helicase Machinery gene
  DQM45_RS07925 (NCTC10999_01613) - 1587985..1588614 (+) 630 WP_003085293.1 YigZ family protein -
  DQM45_RS07930 (NCTC10999_01614) cysK 1588727..1589653 (+) 927 WP_003085481.1 cysteine synthase A -
  DQM45_RS07935 (NCTC10999_01615) - 1589687..1590040 (-) 354 WP_003083428.1 S1 RNA-binding domain-containing protein -
  DQM45_RS07940 (NCTC10999_01616) - 1590040..1591440 (-) 1401 WP_003086028.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM45_RS07945 (NCTC10999_01617) - 1591474..1592115 (-) 642 WP_003084661.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 50178.38 Da        Isoelectric Point: 9.8867

>NTDB_id=1139809 DQM45_RS07920 WP_003084125.1 1586628..1587929(-) (comFA/cflA) [Streptococcus porcinus strain NCTC10999]
MEHLENLYGRIFTANQISYEARKIARTKDSFECDGKDYYCGRCFTKADKDHLLPNGHYYCRRCLIFGRVQSHDKLYYFPA
QPFPKGNYLKWKGALTPYQESISKQLVENYYLEKRSLVYAVTGAGKTEMIYRIIKEVVNSGKWVALVSPRIDVCIEVHKR
LSRDFSCQIVLMHAESESYHRAPLVIATTHQLLKFYKAFHLIIIDEVDSFPFVDNPLLNRAVMSALTEEGRLIYLTATST
KFLEREVINGKLTKITLPRRFHSNPLIVPDFQLIFNLQRYLDRDKLPHKLFSAIQKQTTFLYPLLIFFPIIEKGQKFYET
LVKIFPSHKIGYVSSQTIKRKELIENFRRGELSILVTTTILERGVTIPSVDVFVILAHHHLFTSSSLIQIAGRVGRSVDR
PTGKVIFFHEGVSSAMYRARKEIRGLNKEAYGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1139809 DQM45_RS07920 WP_003084125.1 1586628..1587929(-) (comFA/cflA) [Streptococcus porcinus strain NCTC10999]
ATGGAACATTTAGAGAATTTATATGGTCGCATATTTACAGCTAATCAAATTAGCTATGAAGCACGAAAGATTGCAAGAAC
TAAAGATAGTTTTGAGTGTGACGGTAAGGATTATTATTGCGGACGTTGTTTTACTAAAGCCGATAAGGATCACTTACTGC
CTAATGGACACTACTATTGCAGAAGGTGTTTAATTTTTGGCCGAGTGCAAAGTCATGACAAGCTCTATTATTTCCCTGCT
CAGCCATTTCCTAAAGGGAATTATCTCAAGTGGAAAGGAGCTTTAACACCTTATCAAGAAAGTATTTCTAAACAATTGGT
TGAAAATTATTATTTAGAAAAACGGAGCTTGGTCTATGCTGTTACAGGAGCAGGTAAAACAGAGATGATTTATAGAATTA
TCAAAGAAGTAGTTAATAGCGGGAAATGGGTGGCTTTGGTCAGTCCGAGAATTGATGTCTGTATTGAAGTTCATAAGCGC
TTAAGCCGTGACTTCTCATGTCAGATTGTTTTGATGCATGCAGAGTCAGAAAGTTATCATAGAGCTCCGCTCGTTATTGC
AACAACTCATCAATTATTGAAGTTTTATAAGGCATTTCATTTGATTATTATTGATGAGGTAGACTCTTTTCCATTTGTTG
ATAACCCACTTCTAAATCGTGCTGTTATGTCAGCGTTGACAGAGGAAGGTCGATTAATCTATTTGACAGCTACCTCCACA
AAGTTTCTAGAGAGGGAAGTGATAAATGGTAAACTGACCAAAATAACTCTACCCAGACGATTTCATAGTAATCCTTTGAT
AGTACCTGATTTTCAATTGATTTTTAATCTTCAAAGATATTTGGATAGGGATAAACTCCCTCATAAGCTATTTTCTGCCA
TACAAAAACAGACTACTTTTCTCTATCCACTTTTGATTTTTTTTCCTATCATAGAGAAAGGTCAGAAATTCTATGAAACT
TTAGTAAAAATATTTCCTAGTCACAAAATAGGTTATGTAAGTAGCCAAACTATTAAACGTAAAGAATTGATTGAGAACTT
TCGTCGAGGGGAGTTATCAATTCTTGTTACGACTACGATTCTAGAAAGAGGTGTTACGATTCCTAGTGTGGATGTCTTTG
TAATATTAGCGCACCATCATCTTTTTACCTCTTCAAGTCTCATTCAAATAGCTGGGCGGGTTGGGAGATCTGTCGATCGC
CCAACTGGTAAAGTGATCTTTTTTCATGAGGGAGTGAGCTCTGCTATGTATAGAGCAAGAAAAGAAATAAGAGGCTTAAA
TAAGGAAGCTTATGGGCTATAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(304-396)

Type III restriction enzyme, res subunit (ResIII)

(95-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0HAX3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae D39

54.028

97.46

0.527
  comFA/cflA Streptococcus pneumoniae R6

54.028

97.46

0.527
  comFA/cflA Streptococcus pneumoniae TIGR4

54.028

97.46

0.527
  comFA/cflA Streptococcus pneumoniae Rx1

54.028

97.46

0.527
  comFA/cflA Streptococcus mitis SK321

52.941

98.152

0.52
  comFA/cflA Streptococcus mitis NCTC 12261

52.471

98.152

0.515
  comFA Lactococcus lactis subsp. cremoris KW2

49.744

90.069

0.448
  comFA Latilactobacillus sakei subsp. sakei 23K

38.215

100

0.386

Multiple sequence alignment