Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQM63_RS08650 Genome accession   NZ_LS483385
Coordinates   1734960..1735649 (-) Length   229 a.a.
NCBI ID   WP_002903255.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1729960..1740649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS08635 (NCTC7863_01701) nrdR 1731002..1731475 (-) 474 WP_002894570.1 transcriptional regulator NrdR -
  DQM63_RS08640 (NCTC7863_01702) - 1731647..1732462 (-) 816 WP_002903253.1 endonuclease/exonuclease/phosphatase family protein -
  DQM63_RS08645 (NCTC7863_01703) - 1732480..1734672 (-) 2193 WP_002903254.1 PTS transporter subunit IIBC -
  DQM63_RS08650 (NCTC7863_01704) covR 1734960..1735649 (-) 690 WP_002903255.1 response regulator transcription factor Regulator
  DQM63_RS08655 (NCTC7863_01705) gndA 1735659..1737083 (-) 1425 WP_002899701.1 NADP-dependent phosphogluconate dehydrogenase -
  DQM63_RS11760 - 1737272..1737433 (-) 162 WP_002899700.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DQM63_RS08665 (NCTC7863_01706) - 1737459..1737857 (-) 399 WP_002899698.1 hypothetical protein -
  DQM63_RS08670 (NCTC7863_01707) - 1737854..1739758 (-) 1905 WP_002899697.1 ATP-binding protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26338.29 Da        Isoelectric Point: 5.1934

>NTDB_id=1139642 DQM63_RS08650 WP_002903255.1 1734960..1735649(-) (covR) [Streptococcus sanguinis strain NCTC7863]
MAKRILLVENEKNLARFVSLELQKESFLVDLAETGQEGLALAKDADYDLLLLNYNLQDMTASDFAQQLSLIKPASVIIVL
ASREEIAEQQEAIQHFAVSYVVKPFIISDLVERVSVIFRGRDFIDQHCSLLKIPTSYRNLRVDIKNHTVYRGEEVIALTR
REYDLLVTLMGSNKVMSREQLLERVWKYESATETNVVDVYIRYLRSKIDVEGQPSYIRTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1139642 DQM63_RS08650 WP_002903255.1 1734960..1735649(-) (covR) [Streptococcus sanguinis strain NCTC7863]
ATGGCAAAGCGAATTTTACTAGTAGAAAATGAAAAAAATCTTGCCCGATTTGTGAGTTTGGAACTGCAAAAGGAAAGCTT
TCTTGTAGATTTAGCTGAGACTGGTCAAGAGGGGCTAGCTCTGGCTAAAGATGCCGATTATGACTTGCTTCTGCTCAACT
ATAATCTTCAGGATATGACTGCCAGCGACTTTGCTCAGCAGCTGAGTTTGATTAAGCCAGCGTCCGTCATTATCGTCCTG
GCTAGTCGCGAAGAGATTGCAGAGCAGCAGGAAGCAATCCAGCATTTTGCCGTTTCATACGTAGTCAAGCCTTTCATTAT
CAGTGACTTAGTGGAGCGTGTCTCTGTCATTTTCCGCGGGCGTGACTTTATCGACCAGCACTGCAGCCTCTTGAAAATTC
CGACCTCTTATAGGAATCTGCGAGTGGATATTAAAAATCACACGGTTTACCGTGGTGAGGAAGTTATCGCACTGACGCGG
CGGGAGTACGATCTGTTGGTGACCCTGATGGGCAGCAATAAGGTCATGAGCCGTGAGCAGCTGCTGGAGCGTGTCTGGAA
GTACGAGAGTGCAACGGAGACCAACGTTGTAGATGTTTATATTCGTTATCTGCGCAGTAAAATTGATGTGGAAGGGCAGC
CAAGCTATATCAGAACCGTTCGCGGTGTTGGTTATGCCATGCAAGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

48.035

100

0.48

Multiple sequence alignment