Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQM67_RS02475 Genome accession   NZ_LS483383
Coordinates   483365..484054 (+) Length   229 a.a.
NCBI ID   WP_005590898.1    Uniprot ID   A0AAV3EDD4
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 478365..489054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS02455 (NCTC12479_00468) - 478933..479424 (+) 492 WP_005590904.1 HD domain-containing protein -
  DQM67_RS02460 (NCTC12479_00469) - 479444..480127 (+) 684 WP_005590903.1 Bax inhibitor-1/YccA family protein -
  DQM67_RS02465 (NCTC12479_00470) - 480309..481772 (+) 1464 WP_005592424.1 flotillin family protein -
  DQM67_RS02470 (NCTC12479_00471) gndA 481931..483355 (+) 1425 WP_005590899.1 NADP-dependent phosphogluconate dehydrogenase -
  DQM67_RS02475 (NCTC12479_00472) covR 483365..484054 (+) 690 WP_005590898.1 response regulator transcription factor Regulator
  DQM67_RS02480 (NCTC12479_00473) - 484150..484632 (-) 483 WP_005590897.1 S-ribosylhomocysteine lyase -
  DQM67_RS02485 (NCTC12479_00474) - 484909..486522 (+) 1614 WP_005590895.1 ribonuclease Y -
  DQM67_RS02490 - 486622..486732 (+) 111 Protein_427 SAM-dependent methyltransferase -
  DQM67_RS02495 (NCTC12479_00475) - 486964..487560 (+) 597 WP_005590894.1 TetR/AcrR family transcriptional regulator -
  DQM67_RS02500 (NCTC12479_00476) - 487560..488513 (+) 954 WP_005590893.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26566.59 Da        Isoelectric Point: 6.2793

>NTDB_id=1139491 DQM67_RS02475 WP_005590898.1 483365..484054(+) (covR) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MAKRILLVENEKNLARFVTLELQKEAFLLDVVETGSQGLALARENDYDLFLLNYDLQDMTASEFARQLSLFKPASVIIVL
ASREEIKEHADEIQRFAVSYTVKPFIISDLVEKVSDIFRGRDFIDQHCSKLKTPTAYRNLRVDLKNHIVYRGEEVIALTR
REYDLLVTLMSNQKVMSREQLLERVWKYEGATETNVVDVYIRYLRSKIDIAGQTSYIKTVRGIGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1139491 DQM67_RS02475 WP_005590898.1 483365..484054(+) (covR) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGGCAAAGCGAATTTTATTAGTAGAAAATGAAAAGAATCTTGCACGATTTGTGACTTTGGAACTGCAAAAGGAAGCATT
TCTTTTGGATGTAGTTGAGACAGGCAGTCAAGGTTTGGCACTAGCTAGAGAAAATGACTATGATCTATTTTTGCTTAATT
ATGACTTGCAGGATATGACCGCTAGTGAGTTTGCTAGGCAACTGAGTTTGTTCAAGCCGGCTTCAGTCATTATCGTCTTA
GCCAGCCGTGAAGAAATCAAAGAACATGCAGATGAGATTCAGCGCTTTGCTGTTTCCTATACCGTCAAACCTTTTATTAT
CAGTGATTTGGTTGAGAAAGTATCCGATATCTTTCGAGGTCGGGACTTTATTGACCAGCATTGTAGCAAGCTGAAAACAC
CGACTGCTTACCGCAATCTACGAGTTGATTTGAAAAATCATATCGTCTATCGTGGAGAGGAAGTGATTGCCTTGACAAGA
CGGGAATATGATCTACTAGTGACGCTGATGAGCAACCAAAAGGTCATGAGCCGCGAGCAGCTTCTGGAACGTGTCTGGAA
GTATGAAGGCGCCACTGAAACCAACGTAGTCGATGTCTATATTCGCTATCTACGTAGTAAGATTGATATTGCTGGTCAGA
CTAGCTATATCAAAACTGTCCGTGGCATTGGCTATGCTATGCAGGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.725

100

0.467

Multiple sequence alignment