Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM69_RS08825 Genome accession   NZ_LS483381
Coordinates   1815307..1816605 (-) Length   432 a.a.
NCBI ID   WP_019771102.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1810307..1821605
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS08815 (NCTC10921_01754) hpf 1814015..1814563 (-) 549 WP_002960280.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQM69_RS08820 (NCTC10921_01755) - 1814639..1815307 (-) 669 WP_002960281.1 ComF family protein -
  DQM69_RS08825 (NCTC10921_01756) comFA/cflA 1815307..1816605 (-) 1299 WP_019771102.1 DEAD/DEAH box helicase Machinery gene
  DQM69_RS08830 (NCTC10921_01757) - 1816652..1817290 (+) 639 WP_094966549.1 YigZ family protein -
  DQM69_RS08835 (NCTC10921_01758) cysK 1817390..1818319 (+) 930 WP_019769631.1 cysteine synthase A -
  DQM69_RS08840 (NCTC10921_01759) - 1818538..1818888 (-) 351 WP_109982744.1 S1 RNA-binding domain-containing protein -
  DQM69_RS08845 (NCTC10921_01760) - 1818888..1820285 (-) 1398 WP_109982745.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM69_RS08850 (NCTC10921_01761) - 1820389..1821039 (-) 651 WP_019770084.1 response regulator -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49557.51 Da        Isoelectric Point: 10.1615

>NTDB_id=1139410 DQM69_RS08825 WP_019771102.1 1815307..1816605(-) (comFA/cflA) [Streptococcus sobrinus strain NCTC10921]
MKDMKNYYGWQLTADQVPDDLRDKASVLPATIKKSGKYYCARCNHLLLPEWTLPDGSSYCRNCIVFGRLTTLDHLYYFEQ
KPFTKGAYLRWQGQLTPYQKEVSDILLEAVEKRENILVHAVTGSGKTEMIYRALANRLAKGKVVALVSPRIDVCRELYQR
LSRDFSCPISLLYANSEDYHRSPFLISTVHQLFKFRQAFDLIVIDEVDAFPFVDDQSLYHAVANALKPQGSKIFLTATST
DNLEKQVKKGQLREVHLARRFHANPLVSPSFVWLGDLDKKMTKGLIPVKLGQAIRQQRQTGFPLLLFYPTIVEGEQFARL
LQKYFPKEKIGFVSSRSQDRLELVQDFREGKLDILVSTTILERGVTFPKIDLFVLNAHHKLYTKSSLIQIAGRVGRSSKR
PNGLLRFYHSGVTRAMRRALQDIKLMNKKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1139410 DQM69_RS08825 WP_019771102.1 1815307..1816605(-) (comFA/cflA) [Streptococcus sobrinus strain NCTC10921]
ATGAAAGATATGAAAAATTACTATGGCTGGCAGTTGACTGCCGATCAAGTCCCGGACGACTTACGTGATAAGGCTTCGGT
CCTGCCTGCTACAATTAAAAAATCTGGGAAATATTACTGTGCTCGCTGCAACCATCTCTTATTGCCAGAGTGGACATTGC
CAGACGGTTCGTCTTATTGTCGCAACTGTATTGTTTTTGGCCGCTTGACCACTCTGGATCACCTTTATTATTTTGAGCAA
AAGCCTTTCACCAAAGGAGCTTATCTGCGTTGGCAGGGACAATTAACGCCTTACCAGAAGGAAGTTTCAGATATTCTCCT
TGAAGCAGTTGAAAAAAGAGAAAATATTTTAGTTCATGCTGTTACGGGCTCAGGTAAGACCGAGATGATTTACCGTGCTC
TAGCCAATCGACTTGCTAAAGGAAAGGTAGTCGCTTTAGTTAGCCCAAGAATTGACGTTTGCCGTGAGCTTTATCAACGT
CTTAGTCGTGATTTTAGCTGTCCGATTTCCCTCTTATATGCCAATTCAGAAGACTATCACCGCTCTCCCTTTTTGATTTC
AACCGTCCATCAACTCTTTAAATTTCGCCAGGCCTTTGACCTCATTGTGATTGACGAGGTTGATGCCTTTCCTTTTGTGG
ACGATCAGAGCCTCTACCATGCCGTAGCCAATGCCCTCAAGCCCCAAGGATCAAAAATCTTTCTGACAGCCACCTCAACT
GATAATTTAGAGAAACAAGTCAAGAAGGGGCAACTCAGAGAGGTTCATCTAGCCCGACGCTTCCATGCCAATCCCCTTGT
CTCGCCATCCTTTGTCTGGCTGGGGGATTTGGATAAAAAGATGACCAAGGGCTTAATTCCAGTCAAGCTTGGCCAGGCTA
TCCGTCAACAGAGACAAACAGGCTTTCCGCTTTTGCTTTTTTATCCGACGATTGTTGAGGGAGAGCAGTTTGCTCGTCTC
TTACAAAAATATTTTCCCAAGGAGAAGATTGGCTTTGTCTCCAGTCGCTCCCAAGACCGCTTGGAGCTAGTTCAAGACTT
TCGAGAGGGCAAGTTAGATATCCTAGTTTCGACGACAATTCTAGAAAGAGGGGTTACCTTCCCCAAAATTGATCTCTTTG
TTTTGAATGCTCACCATAAGCTTTATACAAAATCATCCTTGATTCAAATTGCTGGCCGCGTCGGACGCAGTAGTAAGCGA
CCAAATGGCCTCCTGCGATTTTACCACTCAGGGGTGACACGAGCCATGCGACGGGCTTTGCAGGATATTAAACTGATGAA
TAAAAAAGGAGGCTTTTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

DEAD/DEAH box helicase (DEAD)

(96-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

54.398

100

0.544
  comFA/cflA Streptococcus pneumoniae Rx1

53.241

100

0.532
  comFA/cflA Streptococcus pneumoniae D39

53.241

100

0.532
  comFA/cflA Streptococcus pneumoniae R6

53.241

100

0.532
  comFA/cflA Streptococcus pneumoniae TIGR4

53.009

100

0.53
  comFA/cflA Streptococcus mitis NCTC 12261

53.009

100

0.53
  comFA Lactococcus lactis subsp. cremoris KW2

48.622

92.361

0.449
  comFA Latilactobacillus sakei subsp. sakei 23K

35.862

100

0.361

Multiple sequence alignment