Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   DQM69_RS04890 Genome accession   NZ_LS483381
Coordinates   1004757..1005989 (+) Length   410 a.a.
NCBI ID   WP_019781461.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 999757..1010989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS04860 (NCTC10921_00953) - 999780..1000670 (+) 891 WP_002963151.1 lactate/malate family dehydrogenase -
  DQM69_RS04865 (NCTC10921_00954) - 1000823..1001734 (-) 912 WP_019777081.1 polysaccharide deacetylase family protein -
  DQM69_RS04870 (NCTC10921_00955) - 1001740..1002906 (-) 1167 WP_019777082.1 hydroxymethylglutaryl-CoA synthase -
  DQM69_RS04875 (NCTC10921_00956) - 1003106..1003945 (+) 840 WP_019775453.1 thymidylate synthase -
  DQM69_RS04880 (NCTC10921_00957) - 1004029..1004550 (+) 522 WP_109982577.1 dihydrofolate reductase -
  DQM69_RS04885 (NCTC10921_00958) - 1004565..1004735 (+) 171 WP_002961893.1 hypothetical protein -
  DQM69_RS04890 (NCTC10921_00959) clpX 1004757..1005989 (+) 1233 WP_019781461.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQM69_RS04895 (NCTC10921_00960) yihA 1005999..1006598 (+) 600 WP_109982578.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQM69_RS04900 (NCTC10921_00961) - 1006906..1008279 (+) 1374 WP_021674215.1 amino acid permease -
  DQM69_RS04905 (NCTC10921_00962) mmuM 1008333..1009304 (+) 972 WP_002961900.1 homocysteine S-methyltransferase -
  DQM69_RS04915 (NCTC10921_00964) rplJ 1009634..1010134 (+) 501 WP_019769667.1 50S ribosomal protein L10 -
  DQM69_RS04920 (NCTC10921_00965) rplL 1010208..1010576 (+) 369 WP_002262825.1 50S ribosomal protein L7/L12 -
  DQM69_RS04925 (NCTC10921_00966) - 1010752..1010964 (-) 213 Protein_919 IS3 family transposase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 44953.41 Da        Isoelectric Point: 4.3213

>NTDB_id=1139396 DQM69_RS04890 WP_019781461.1 1004757..1005989(+) (clpX) [Streptococcus sobrinus strain NCTC10921]
MADNQTTNDTMVYCSFCGKNQTEVRKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLQILDDYVIGQV
QAKRALAVAVYNHYKRISFVESAQDEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIVEGTVASVPPQGGRKHPNQEMIQIDT
KNILFIVGGAFDGIEDIVKQRLGEKVIGFGQSNKSLDDDASYMQQIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVR
ILTEPKNALVKQYKTLLSYDGVDLEFDQEALEAIAQKAIERKTGARGLRSIIEETMMDIMFEVPSQEDVTSVEVTKAAVE
GTDKPILKTA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1139396 DQM69_RS04890 WP_019781461.1 1004757..1005989(+) (clpX) [Streptococcus sobrinus strain NCTC10921]
ATGGCAGACAATCAAACAACAAATGATACAATGGTCTATTGCTCATTTTGTGGAAAAAACCAGACAGAGGTCAGAAAAAT
AATTGCTGGTAACGGCGTTTTTATCTGTAATGAATGTGTGGCCCTCTCCCAAGAAATCATCAAAGAGGAGCTAGCTGAAG
AAGTTCTAGCTGACTTGGCGGAAGTTCCAAAACCCAAGGAACTCCTGCAAATCTTGGATGACTATGTTATCGGCCAAGTT
CAAGCAAAAAGAGCTCTGGCAGTTGCCGTTTATAACCATTACAAGCGAATCAGCTTTGTCGAGAGTGCCCAAGATGAGGA
TGTCGATTTGCAGAAATCTAATATTCTCATGATTGGCCCAACTGGTTCCGGTAAGACCTTCTTAGCTCAAACCTTGGCTA
AGAGTCTTAATGTTCCCTTTGCTATTGCGGATGCAACGGCCTTGACTGAAGCTGGATATGTCGGAGAAGATGTGGAGAAT
ATTCTTCTCAAACTGATTCAGGCTGCTGATTTCAATATTGAACGGGCTGAACGAGGCATCATCTATGTCGATGAAATTGA
CAAGATTGCCAAAAAGGGAGAAAATGTCTCCATTACTCGGGATGTCTCTGGTGAAGGGGTGCAACAGGCTCTCTTGAAAA
TTGTTGAAGGAACAGTTGCCAGTGTTCCACCACAAGGCGGGCGCAAGCACCCTAACCAAGAAATGATTCAGATTGACACC
AAGAACATCCTCTTTATTGTCGGAGGTGCCTTTGATGGTATCGAAGATATTGTTAAGCAACGCCTGGGTGAAAAGGTGAT
TGGTTTCGGTCAAAGCAATAAGTCTCTGGATGATGATGCTTCCTATATGCAACAAATTATTTCGGAGGATATTCAAAAAT
TTGGTCTCATTCCTGAATTTATCGGCCGTTTACCTGTCCTGGCTGCCCTTGAGCAGTTGACGGTTGACGATTTAGTGCGG
ATTCTGACTGAACCCAAGAACGCCTTGGTTAAACAGTATAAGACCCTTCTGTCTTATGATGGAGTGGATTTGGAATTTGA
TCAAGAAGCACTTGAAGCGATTGCTCAAAAGGCTATTGAGCGTAAGACTGGTGCTCGGGGCTTGCGTTCCATTATCGAAG
AAACCATGATGGACATCATGTTTGAAGTGCCTAGTCAAGAGGATGTTACCAGCGTTGAAGTGACAAAGGCGGCAGTTGAA
GGGACCGATAAGCCGATTCTCAAGACTGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(13-49)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.756

100

0.898
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.606

97.805

0.563

Multiple sequence alignment