Detailed information NTG1139388

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: DQM69_RS02755
• Genome accession: NZ_LS483381
• Coordinates: 529842..530534 (+)
• Length: 230 a.a.
• NCBI ID: WP_172456394.1
• Uniprot ID: -
• Organism: Streptococcus sobrinus strain NCTC10921
• Function: repress comR expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	530766..532160	529842..530534	flank	232

Gene organization within MGE regions

Location: 529842..532160

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM69_RS02755 (NCTC10921_00538)	covR	529842..530534 (+)	693	WP_172456394.1	response regulator transcription factor	Regulator
DQM69_RS02760 (NCTC10921_00539)	-	530766..532160 (-)	1395	WP_111688001.1	ISNCY family transposase	-

Sequence

Protein

• Length: 230 a.a.
• Molecular weight: 26474.53 Da
• Isoelectric Point: 6.5146

>NTDB_id=1139388 DQM69_RS02755 WP_172456394.1 529842..530534(+) (covR) [Streptococcus sobrinus strain NCTC10921]
MAKRILLIEGEKSLSRLVSLKLQERGYQTVVSQDGKSGLKTAMEKDFELIFIDLKLPDQDGLELMQQLRGHKSVPVVLMV
GREDVATLLPKTDNLADDYLIKPFAVEELLDKVDETFQRKDFKRRKQSTSQTTAYQDLILDEANRSVIRKGESIALTKRE
FALLSTLLRHINMVMTREELLDYVWSYSDGTIETNVVDVYVRYLRGKIDIPGQESYIQTVRGLGYVIRER

Nucleotide

• Length: 693 bp

>NTDB_id=1139388 DQM69_RS02755 WP_172456394.1 529842..530534(+) (covR) [Streptococcus sobrinus strain NCTC10921]
ATGGCAAAACGCATTCTATTGATTGAAGGCGAAAAAAGTTTATCACGTTTGGTATCCTTAAAACTACAGGAAAGGGGCTA
TCAAACAGTTGTCAGTCAAGATGGGAAATCAGGCTTAAAAACAGCCATGGAAAAGGATTTTGAACTAATTTTTATTGATT
TAAAACTCCCAGACCAAGATGGTTTGGAACTGATGCAGCAACTCAGGGGACATAAATCTGTACCAGTTGTCCTGATGGTT
GGTCGGGAAGATGTAGCAACCCTTCTCCCTAAAACTGACAACTTGGCCGATGATTATTTGATTAAGCCCTTTGCGGTGGA
AGAATTACTTGATAAGGTTGATGAAACCTTTCAGCGAAAAGATTTTAAACGCCGGAAGCAATCAACCAGCCAGACAACAG
CTTATCAAGATTTGATTTTGGATGAGGCTAACCGCTCAGTTATTCGCAAAGGGGAGTCCATTGCTCTGACTAAAAGAGAG
TTTGCTTTGCTATCAACTCTTTTACGGCATATCAATATGGTGATGACCCGTGAGGAGTTGTTAGATTATGTCTGGAGTTA
TAGTGATGGGACAATTGAGACCAATGTTGTTGATGTTTACGTACGCTATCTTCGAGGTAAGATTGATATCCCTGGCCAAG
AATCTTATATTCAAACCGTGCGAGGTCTGGGTTATGTGATTCGTGAGCGTTGA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (151-226)

• Response regulator receiver domain (Response_reg) (5-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	54.783	100	0.548
covR	Lactococcus lactis subsp. lactis strain DGCC12653	49.345	99.565	0.491