Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM75_RS07725 Genome accession   NZ_LS483380
Coordinates   1629982..1631304 (-) Length   440 a.a.
NCBI ID   WP_111692701.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1624982..1636304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS07710 (NCTC11824_01553) - 1627223..1628620 (+) 1398 WP_111692170.1 ISNCY-like element ISSeq2 family transposase -
  DQM75_RS07715 (NCTC11824_01554) hpf 1628718..1629266 (-) 549 WP_014623350.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQM75_RS07720 (NCTC11824_01555) - 1629342..1629923 (-) 582 WP_111692700.1 ComF family protein -
  DQM75_RS07725 (NCTC11824_01556) comFA/cflA 1629982..1631304 (-) 1323 WP_111692701.1 DEAD/DEAH box helicase Machinery gene
  DQM75_RS07730 (NCTC11824_01557) - 1631360..1632001 (+) 642 WP_043031300.1 YigZ family protein -
  DQM75_RS07735 (NCTC11824_01558) cysK 1632122..1633048 (+) 927 WP_012679990.1 cysteine synthase A -
  DQM75_RS07740 (NCTC11824_01559) - 1633435..1633797 (-) 363 WP_111692702.1 S1 RNA-binding domain-containing protein -
  DQM75_RS07745 (NCTC11824_01560) - 1633797..1635197 (-) 1401 WP_111692703.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM75_RS07750 (NCTC11824_01561) - 1635230..1635871 (-) 642 WP_021321066.1 response regulator -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 50014.12 Da        Isoelectric Point: 9.5419

>NTDB_id=1139349 DQM75_RS07725 WP_111692701.1 1629982..1631304(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MENIENYYGRLLPERQCPKAVSVWACSLQSMIAKKGTLYCQRCSSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
APFPKAHYLRWQGQLTTYQGAVSHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVDKGGWVCIASPRVDVCIELEKR
LSRDFSCQVCLMHAESEVYHRSPIIVATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKADAVTVYLTATST
RDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLEAINRGKLPRRFITLVKKQRATGYPLLIFFPIIELAEQCCQL
LQKYFPKETIAHASSQSSNRMTIIEQFRQGQITILISTTILERGVTFPTVDVFVLLANHHLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISQAMLKAVREIKDMNQKGYQNELSTLPQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1139349 DQM75_RS07725 WP_111692701.1 1629982..1631304(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGGAGAATATCGAAAATTACTATGGACGTCTTTTACCCGAAAGGCAATGCCCAAAGGCTGTTTCTGTCTGGGCTTGCAG
CTTACAAAGCATGATCGCTAAAAAAGGAACATTATACTGCCAACGCTGTAGCAGCTTAATTGAGAAAGCTCATCAGCTAC
CTAGCGGTGCTTACTATTGTAGAGCCTGTCTCGTTTTTGGTCGAAACCAATCTGATCGGCCCTTGCTCTATTTTCCACCG
GCTCCTTTTCCAAAGGCACATTATCTGAGGTGGCAAGGACAGCTCACAACATATCAGGGAGCTGTCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACACTGGTTCATGCCGTTACCGGCGCTGGTAAAACAGAGATGATGTATGAAGCCA
TTGCAGCAGTTGTTGATAAGGGGGGTTGGGTCTGCATTGCTAGTCCACGAGTTGATGTCTGCATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAGTCTGCCTTATGCATGCTGAGTCAGAGGTTTATCATAGAAGTCCCATTATCGTTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTCCCCTTTGTCA
ATAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAGCAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AGAGATTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACGTTGGCAAGAAGATTCCATGGCAAGCCCTTAGT
TGTTCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGGCTATCAATCGCGGGAAATTGCCTAGAAGGTTCATCACCCTAG
TCAAAAAACAAAGGGCAACCGGCTATCCTCTTTTAATCTTTTTTCCGATTATTGAGCTGGCTGAGCAATGCTGTCAGCTG
TTGCAAAAGTATTTTCCTAAGGAAACTATTGCTCATGCTTCCAGTCAGTCATCAAATCGAATGACTATCATTGAGCAATT
CAGACAAGGACAAATCACTATACTTATATCAACAACCATTTTGGAAAGAGGTGTGACCTTTCCAACCGTAGATGTCTTTG
TCTTATTAGCCAATCATCACCTTTACACAAGCAGCAGTCTTATTCAAATTTCAGGTCGCGTTGGGCGCTCTTTGGAAAGA
CCTGAAGGACAGGTGCTATTTTTTCATGATGGTATTAGCCAGGCTATGCTTAAGGCAGTGCGGGAGATAAAGGACATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGCCACAATAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(112-244)

Helicase conserved C-terminal domain (Helicase_C)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae R6

52.471

96.591

0.507
  comFA/cflA Streptococcus pneumoniae Rx1

52.471

96.591

0.507
  comFA/cflA Streptococcus pneumoniae D39

52.471

96.591

0.507
  comFA/cflA Streptococcus pneumoniae TIGR4

52.471

96.591

0.507
  comFA/cflA Streptococcus mitis SK321

52.471

96.591

0.507
  comFA/cflA Streptococcus mitis NCTC 12261

52.235

96.591

0.505
  comFA Lactococcus lactis subsp. cremoris KW2

48.214

89.091

0.43

Multiple sequence alignment