Detailed information NTG1139284

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQM61_RS03685
• Genome accession: NZ_LS483379
• Coordinates: 699146..700375 (+)
• Length: 409 a.a.
• NCBI ID: WP_023609877.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10874
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 694146..705375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM61_RS03660 (NCTC10874_00718)	-	694762..696039 (-)	1278	WP_020833420.1	hydroxymethylglutaryl-CoA reductase, degradative	-
DQM61_RS03665 (NCTC10874_00719)	-	696026..697201 (-)	1176	WP_023609855.1	hydroxymethylglutaryl-CoA synthase	-
DQM61_RS03670 (NCTC10874_00720)	-	697410..698249 (+)	840	WP_011017679.1	thymidylate synthase	-
DQM61_RS03675 (NCTC10874_00721)	-	698329..698826 (+)	498	WP_002984955.1	dihydrofolate reductase	-
DQM61_RS03685 (NCTC10874_00723)	clpX	699146..700375 (+)	1230	WP_023609877.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQM61_RS03690 (NCTC10874_00724)	yihA	700385..700984 (+)	600	WP_011184414.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQM61_RS03695 (NCTC10874_00725)	-	701132..701875 (+)	744	WP_002984942.1	hypothetical protein	-
DQM61_RS03700 (NCTC10874_00726)	-	701933..704032 (-)	2100	WP_023609853.1	AAA family ATPase	-
DQM61_RS03705 (NCTC10874_00727)	rpiA	704411..705094 (+)	684	WP_010922176.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45045.62 Da
• Isoelectric Point: 4.6616

>NTDB_id=1139284 DQM61_RS03685 WP_023609877.1 699146..700375(+) (clpX) [Streptococcus pyogenes strain NCTC10874]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKISDLIRI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1139284 DQM61_RS03685 WP_023609877.1 699146..700375(+) (clpX) [Streptococcus pyogenes strain NCTC10874]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAATATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575