Detailed information NTG1139119

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DQM54_RS05580
• Genome accession: NZ_LS483375
• Coordinates: 1137339..1138568 (-)
• Length: 409 a.a.
• NCBI ID: WP_008808666.1
• Uniprot ID: A0AAP2K4Q6
• Organism: Streptococcus gordonii strain NCTC3165
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1132099..1152517	1137339..1138568	within	0

Gene organization within MGE regions

Location: 1132099..1152517

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM54_RS05550 (NCTC3165_01105)	-	1132099..1133265 (-)	1167	WP_111723721.1	ATP-grasp domain-containing protein	-
DQM54_RS05555 (NCTC3165_01106)	-	1133278..1134018 (-)	741	WP_020992631.1	esterase family protein	-
DQM54_RS05560 (NCTC3165_01107)	-	1134068..1134892 (-)	825	WP_008808670.1	alpha/beta hydrolase	-
DQM54_RS05565 (NCTC3165_01108)	-	1134986..1135783 (-)	798	WP_111723722.1	formate/nitrite transporter family protein	-
DQM54_RS05570 (NCTC3165_01109)	-	1135912..1136601 (-)	690	WP_008808668.1	glucosaminidase domain-containing protein	-
DQM54_RS05575 (NCTC3165_01110)	yihA	1136736..1137329 (-)	594	WP_008808667.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DQM54_RS05580 (NCTC3165_01111)	clpX	1137339..1138568 (-)	1230	WP_008808666.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DQM54_RS05590 (NCTC3165_01112)	-	1138778..1139290 (-)	513	WP_008808665.1	dihydrofolate reductase	-
DQM54_RS05595 (NCTC3165_01113)	-	1139436..1139936 (-)	501	WP_008808664.1	hypothetical protein	-
DQM54_RS05600 (NCTC3165_01114)	-	1140067..1140906 (-)	840	WP_008808663.1	thymidylate synthase	-
DQM54_RS05605 (NCTC3165_01115)	-	1141006..1141965 (-)	960	WP_008808662.1	ROK family glucokinase	-
DQM54_RS05610 (NCTC3165_01116)	-	1142140..1142985 (-)	846	WP_111723723.1	alpha/beta hydrolase	-
DQM54_RS05615 (NCTC3165_01117)	-	1143099..1143701 (-)	603	WP_045774036.1	lysozyme family protein	-
DQM54_RS05620 (NCTC3165_01118)	-	1143701..1144675 (-)	975	WP_111723724.1	nucleoid-associated protein	-
DQM54_RS05625 (NCTC3165_01119)	glyA	1144677..1145939 (-)	1263	WP_008808658.1	serine hydroxymethyltransferase	-
DQM54_RS05630 (NCTC3165_01120)	-	1145987..1146577 (-)	591	WP_048775981.1	L-threonylcarbamoyladenylate synthase	-
DQM54_RS05635 (NCTC3165_01121)	prmC	1146570..1147400 (-)	831	WP_008808656.1	peptide chain release factor N(5)-glutamine methyltransferase	-
DQM54_RS05640 (NCTC3165_01122)	prfA	1147400..1148479 (-)	1080	WP_012000560.1	peptide chain release factor 1	-
DQM54_RS05645 (NCTC3165_01123)	-	1148512..1149087 (-)	576	WP_111723725.1	thymidine kinase	-
DQM54_RS05650 (NCTC3165_01124)	-	1149209..1149391 (+)	183	WP_001117401.1	4-oxalocrotonate tautomerase	-
DQM54_RS05655 (NCTC3165_01125)	-	1149505..1150770 (-)	1266	WP_037622361.1	nucleobase:cation symporter-2 family protein	-
DQM54_RS05660 (NCTC3165_01126)	-	1150772..1151353 (-)	582	WP_111723726.1	xanthine phosphoribosyltransferase	-
DQM54_RS05665 (NCTC3165_01127)	guaC	1151534..1152517 (-)	984	WP_012000563.1	GMP reductase	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45650.21 Da
• Isoelectric Point: 4.4870

>NTDB_id=1139119 DQM54_RS05580 WP_008808666.1 1137339..1138568(-) (clpX) [Streptococcus gordonii strain NCTC3165]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1139119 DQM54_RS05580 WP_008808666.1 1137339..1138568(-) (clpX) [Streptococcus gordonii strain NCTC3165]
ATGCCTACCAATCGTAATGAAGAGATGATGGTATATTGTTCATTCTGTGGGAAGAACCAAGATGAGGTTCAAAAGATTAT
TGCGGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCACAAGAAATTATCCGTGAAGAATTAGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGTCAAGAACGT
GCTAAAAGAGCGCTAGCTGTAGCGGTATATAATCACTACAAGCGTATTAATTTTCATGACAGTCGCGAAGAAGATGATGT
TGAATTACAAAAATCAAATATCTTAATGATCGGTCCAACGGGATCTGGGAAGACTTTTCTTGCTCAGACCTTAGCTAGAA
GTTTAAATGTGCCTTTTGCTATTGCTGATGCGACAGCTTTAACAGAGGCTGGTTATGTCGGAGAAGACGTTGAAAATATC
CTTTTAAAACTTTTACAGGCGGCTGATTTCAATATTGAACGTGCAGAACGAGGAATCATCTACGTAGATGAGATTGATAA
GATCGCTAAAAAGAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAAGCTCTCTTAAAAATTA
TCGAGGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAACATCCGCAGCAAGAAATGATTCAGGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGGATTGAAGAAATTGTAAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATCGATGAAAACGAGTCCTACATGCAGGCTATTATTGCTGAAGATATTCAAAAATTTG
GAATTATTCCTGAATTAATTGGCCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGATGACTTGGTTCGTATT
CTTCGTGAGCCAAAGAATGCTTTGGTTAAACAATACCAGGCTCTCTTGTCTTACGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGGGCCCGTGGTCTACGTTCTATCATCGAAGAAA
CCATGATGGATGTTATGTTTGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCAGAATTACAAAGGAAGCCGTTGATGGT
ACGGATAAACCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-389)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	85.575	100	0.856
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.105	98.044	0.57